Infertility tests normal – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 02 Jul 2026 04:04:17 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.1 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Infertility tests normal – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Micronised progesterone luteal-phase support improves live birth rates in women with unexplained infertility https://clinicaltrials.eu/trial/micronised-progesterone-luteal-phase-support-improves-live-birth-rates-in-women-with-unexplained-infertility/ Thu, 02 Jul 2026 04:04:17 +0000 https://clinicaltrials.eu/trial/micronised-progesterone-luteal-phase-support-improves-live-birth-rates-in-women-with-unexplained-infertility/ The study focuses on couples where the woman has unexplained infertility, meaning they have been trying to become pregnant for a year or more without a clear medical reason. The medication being tested is a soft vaginal capsule that contains micronised progesterone, given during the luteal phase (the part of the menstrual cycle after ovulation) to see if it helps achieve a live birth. A matching placebo capsule that looks the same but does not contain the hormone is also used.

The purpose is to find out whether adding this hormone support increases the chance of a baby being born alive compared with taking no active medication. Participants are randomly assigned to receive either the hormone capsule or the placebo for up to six months while trying to become pregnant naturally. Pregnancy outcomes, any side effects, and quality of life are recorded, and participants are followed for up to 18 months after the start of the study.

]]> Study on Progesterone for Improving Birth Rates in Couples with Unexplained Infertility Undergoing Mild Ovarian Stimulation and Intrauterine Insemination https://clinicaltrials.eu/trial/study-on-progesterone-for-improving-birth-rates-in-couples-with-unexplained-infertility-undergoing-mild-ovarian-stimulation-and-intrauterine-insemination/ Wed, 29 Apr 2026 14:24:54 +0000 https://clinicaltrials.eu/trial/study-on-progesterone-for-improving-birth-rates-in-couples-with-unexplained-infertility-undergoing-mild-ovarian-stimulation-and-intrauterine-insemination/ This clinical trial is focused on studying the effects of a treatment for couples experiencing unexplained infertility. The treatment being tested is called Utrogestan, which is a soft vaginal capsule containing micronised progesterone. Progesterone is a hormone that plays a crucial role in the menstrual cycle and in maintaining the early stages of pregnancy. The study will also use a placebo, which is a capsule that looks like the real medication but does not contain the active ingredient, to compare the effects of the treatment.

The purpose of the study is to determine if adding progesterone support during a specific phase of the menstrual cycle, known as the luteal phase, can increase the chances of a live birth for couples undergoing a fertility treatment called intra-uterine insemination (IUI) with mild ovarian stimulation. This involves using a medication called FSH to gently stimulate the ovaries. The study will follow participants over a period of six months to observe outcomes such as pregnancy rates, live births, and any side effects experienced during the treatment.

Participants in the study will be monitored for various outcomes, including the number of IUI cycles they undergo, any pregnancies that occur, and the overall impact on their quality of life. The study will also assess the cost-effectiveness of adding progesterone support to the treatment. The findings from this study aim to provide valuable insights into improving fertility treatment outcomes for couples facing unexplained infertility.

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