Hypothermia – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 03 Jun 2026 04:05:31 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Hypothermia – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Reducing Body Temperature in Healthy Volunteers Using Pethidine and Buspirone to Prevent Shivering https://clinicaltrials.eu/trial/study-on-reducing-body-temperature-in-healthy-volunteers-using-pethidine-and-buspirone-to-prevent-shivering/ Wed, 29 Apr 2026 15:05:47 +0000 https://clinicaltrials.eu/trial/study-on-reducing-body-temperature-in-healthy-volunteers-using-pethidine-and-buspirone-to-prevent-shivering/ This clinical trial is focused on studying hypothermia, a condition where the body temperature drops below the normal level. The study aims to explore how lowering the surrounding temperature and using specific medications can help manage this condition. The medications being tested include meperidine and buspirone, which are used to prevent shivering, a natural response of the body to cold. Additionally, a placebo is used for comparison purposes.

The purpose of the study is to see how effective these medications are in reducing body temperature without causing shivering. Participants will be exposed to a cold environment in a controlled setting, and their body temperature will be monitored throughout the process. The study will compare the effects of the active medications against the placebo to determine their effectiveness in managing hypothermia.

During the study, participants will receive the medications through different methods, such as intravenous (directly into the vein) or oral (by mouth) administration. The study will last for a short period, and participants will be closely monitored for any changes in their body temperature and overall health. The goal is to gather information on how these treatments can help manage hypothermia safely and effectively.

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