Hepatectomy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:24:02 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Hepatectomy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of lidocaine hydrochloride to reduce side effects from pain medication in patients undergoing open liver surgery https://clinicaltrials.eu/trial/study-of-lidocaine-hydrochloride-to-reduce-side-effects-from-pain-medication-in-patients-undergoing-open-liver-surgery/ Wed, 29 Apr 2026 15:09:24 +0000 https://clinicaltrials.eu/trial/study-of-lidocaine-hydrochloride-to-reduce-side-effects-from-pain-medication-in-patients-undergoing-open-liver-surgery/ This study focuses on patients undergoing an open hepatectomy, which is a major surgical procedure to remove a portion of the liver. The research aims to compare the effects of an infusion of lidocaine hydrochloride with a placebo on side effects caused by opioids, which are strong pain medications, following the surgery. Potential complications being monitored include postoperative nausea and vomiting, hypoxemia, which is a condition where there is not enough oxygen in the blood, and postoperative ileus, a temporary lack of normal muscle contractions in the intestines that prevents the passage of food or gas.

Participants in the study will receive either lidocaine hydrochloride or sodium chloride through an intravenous infusion, meaning the substance is delivered directly into a vein. The study period covers the time around the surgery and the first 48 hours after the breathing tube is removed. Various factors such as pain levels, the amount of pain medication used, the length of time spent in the hospital, and the risk of other issues like pneumonia or acute kidney insufficiency will be observed during the recovery process.

]]> Study on the Effects of Octreotide in Reducing Blood Loss During Laparoscopic Liver Surgery for Patients Undergoing Hepatectomy https://clinicaltrials.eu/trial/study-on-the-effects-of-octreotide-in-reducing-blood-loss-during-laparoscopic-liver-surgery-for-patients-undergoing-hepatectomy/ Wed, 29 Apr 2026 14:24:06 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-octreotide-in-reducing-blood-loss-during-laparoscopic-liver-surgery-for-patients-undergoing-hepatectomy/ This clinical trial is focused on studying the effects of a medication called octreotide during a type of liver surgery known as laparoscopic hepatectomy. This surgery involves removing part of the liver using small incisions and a camera to guide the procedure. The trial aims to observe how octreotide, which is a synthetic version of a natural hormone, affects blood loss during the surgery compared to a placebo. The study will also look at the need for medications that help control blood pressure and heart rate, as well as the requirement for blood transfusions during and after the surgery.

Participants in the study will receive either octreotide or a placebo during their surgery. The trial will monitor several factors, including the amount of blood lost, changes in heart rate and blood pressure, and the need for blood transfusions. Additionally, the study will assess liver function recovery after surgery and any complications that may arise up to three months post-surgery. The goal is to determine if octreotide can help reduce blood loss and improve overall outcomes for patients undergoing this type of liver surgery.

The trial will run until 2026, and it will provide valuable information on the safety and effectiveness of using octreotide in laparoscopic hepatectomy. By understanding how this medication impacts surgery outcomes, healthcare providers can make more informed decisions about its use in managing blood loss and other related factors during liver surgeries.

]]>