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	<title>Hemiparesis &#8211; European Clinical Trials Information Network</title>
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	<title>Hemiparesis &#8211; European Clinical Trials Information Network</title>
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		<title>A study of belzutifan and lenvatinib for patients with von Hippel-Lindau disease-associated tumors or other specific solid tumors.</title>
		<link>https://clinicaltrials.eu/trial/a-study-of-belzutifan-and-lenvatinib-for-patients-with-von-hippel-lindau-disease-associated-tumors-or-other-specific-solid-tumors/</link>
		
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		<pubDate>Thu, 30 Apr 2026 13:08:57 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/a-study-of-belzutifan-and-lenvatinib-for-patients-with-von-hippel-lindau-disease-associated-tumors-or-other-specific-solid-tumors/</guid>

					<description><![CDATA[This study focuses on individuals with various types of cancer, including Renal Cell Carcinoma, Hepatocellular Carcinoma, Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancer, Esophageal Squamous Cell Carcinoma, and Pancreatic Neuroendocrine Tumor. It also includes people with Advanced Pheochromocytoma/Paraganglioma, Advanced Gastrointestinal Stromal Tumor, and certain types of Colorectal Cancer, Endometrial Cancer, or Solid Tumors that have specific [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on individuals with various types of cancer, including <b>Renal Cell Carcinoma</b>, <b>Hepatocellular Carcinoma</b>, <b>Pancreatic Ductal Adenocarcinoma</b>, <b>Biliary Tract Cancer</b>, <b>Esophageal Squamous Cell Carcinoma</b>, and <b>Pancreatic Neuroendocrine Tumor</b>. It also includes people with <b>Advanced Pheochromocytoma/Paraganglioma</b>, <b>Advanced Gastrointestinal Stromal Tumor</b>, and certain types of <b>Colorectal Cancer</b>, <b>Endometrial Cancer</b>, or <b>Solid Tumors</b> that have specific genetic changes called <b>HIF-2α related genetic alterations</b>. Additionally, the research involves patients with <b>von Hippel-Lindau Disease-Associated Tumors</b>, which are tumors caused by a specific genetic condition. The purpose of the study is to evaluate the long-term effectiveness and safety of certain treatments.</p>
<p>The treatments being studied include <b>belzutifan</b>, which is taken as an oral film-coated tablet, and <b>lenvatinib</b>, which is taken as an oral capsule. Participants in the study will continue their current treatment regimen to monitor how the medications work over a longer period of time. The study will track <b>overall survival</b>, which refers to the length of time patients remain alive, and monitor any <b>adverse events</b>, which are side effects or unexpected medical problems that may occur during the treatment.</p>
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