Haemodynamic instability – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 05 Jun 2026 10:50:22 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Haemodynamic instability – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Finding the Right Dose of Dobutamine for Very Preterm Infants with Heart and Blood Flow Issues https://clinicaltrials.eu/trial/finding-the-right-dose-of-dobutamine-for-very-preterm-infants-with-heart-and-blood-flow-issues/ Wed, 29 Apr 2026 14:24:02 +0000 https://clinicaltrials.eu/trial/finding-the-right-dose-of-dobutamine-for-very-preterm-infants-with-heart-and-blood-flow-issues/ This clinical trial is focused on studying the effects of a medication called in very preterm infants who have a condition known as . This condition occurs when the heart and blood vessels are not able to circulate blood effectively, which can be a concern in newborns born before 32 weeks of pregnancy. The purpose of the study is to find the minimum effective dose of needed to improve blood flow in these infants.

is given as a solution through an intravenous infusion, which means it is delivered directly into the bloodstream. The study will observe how well the infants respond to different doses of by measuring the blood flow in a specific part of the body called the superior vena cava (SVC). The goal is to ensure that the blood flow is above a certain level, which indicates better circulation.

The study will monitor the infants for the first 72 hours after birth to see how well they maintain a stable blood flow with the help of . Researchers will also keep track of any side effects or adverse events that may occur during the study. This information will help determine the safest and most effective dose of for improving blood circulation in very preterm infants with .

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