Genitourinary syndrome of menopause – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:37:24 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Genitourinary syndrome of menopause – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effect of Prasterone on Genitourinary Syndrome in Postmenopausal Women with a History of Breast Cancer or Undergoing Anti-Hormonal Therapy https://clinicaltrials.eu/trial/study-on-the-effect-of-prasterone-on-genitourinary-syndrome-in-postmenopausal-women-with-a-history-of-breast-cancer-or-undergoing-anti-hormonal-therapy/ Wed, 29 Apr 2026 15:01:22 +0000 https://clinicaltrials.eu/trial/study-on-the-effect-of-prasterone-on-genitourinary-syndrome-in-postmenopausal-women-with-a-history-of-breast-cancer-or-undergoing-anti-hormonal-therapy/ This clinical trial is focused on studying the effects of a treatment for women who are experiencing symptoms related to menopause and have a history of breast cancer or are currently undergoing treatment for breast cancer. The treatment being tested is a hormonal therapy using a product called Intrarosa, which is a pessary containing the active substance prasterone. This treatment is designed to help improve symptoms such as discomfort in the vaginal, vulvar, or urinary areas, which are collectively known as genitourinary syndrome.

The purpose of the study is to determine if the use of Intrarosa can lead to an improvement in these symptoms for women who have been affected by breast cancer. Participants in the study will receive either the Intrarosa treatment or a placebo. The study will monitor changes in symptoms over a period of time to assess the effectiveness of the treatment. The study will also look at how these symptoms affect the quality of life, including aspects like sexual function and mood.

Throughout the study, participants will undergo regular evaluations to track any changes in their symptoms and overall health. This will include assessments of vaginal health and hormone levels. The study aims to provide valuable information on how Intrarosa can help manage symptoms associated with menopause in women with a history of breast cancer, potentially improving their quality of life.

]]> Study on the Effectiveness of Platelet-Rich Plasma and Hyaluronic Acid vs. Estriol for Women with Menopausal Genitourinary Syndrome https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-platelet-rich-plasma-and-hyaluronic-acid-vs-estriol-for-women-with-menopausal-genitourinary-syndrome/ Wed, 29 Apr 2026 14:29:56 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-platelet-rich-plasma-and-hyaluronic-acid-vs-estriol-for-women-with-menopausal-genitourinary-syndrome/ This clinical trial is focused on studying the effectiveness of two different treatments for genitourinary syndrome of menopause, a condition that affects many women during menopause and can cause symptoms like vaginal dryness, irritation, and discomfort. The study will compare the use of a treatment called Cellular Matrix / A-CP-HA Kit, which is a combination of autologous platelet-rich plasma and non-cross-linked hyaluronic acid, with a local estrogen therapy known as Blissel, which contains estriol in the form of a vaginal gel.

The purpose of the study is to determine which treatment is more effective in improving the symptoms of genitourinary syndrome of menopause. Participants in the study will be randomly assigned to receive either the Cellular Matrix / A-CP-HA Kit or the Blissel vaginal gel. The Cellular Matrix / A-CP-HA Kit involves using a gel that is injected, while the Blissel gel is applied vaginally. The study will last for several months, with participants being monitored at different intervals to assess changes in their symptoms and overall vaginal health.

Throughout the study, participants will have their symptoms evaluated using various health indexes and scales to track improvements. The study aims to provide valuable information on the effectiveness of these treatments, potentially offering better options for managing the symptoms associated with menopause. Participants will be observed by a second, independent observer to ensure unbiased results. The study will help in understanding how these treatments can improve the quality of life for women experiencing this condition.

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