Gastrectomy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:14:32 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Gastrectomy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Fibrin Adhesive to Prevent Leaks After Stomach Cancer Surgery Using Aprotinin, Human Fibrinogen, and Calcium Chloride Dihydrate in Patients Undergoing Total Gastrectomy https://clinicaltrials.eu/trial/study-on-fibrin-adhesive-to-prevent-leaks-after-stomach-cancer-surgery-using-aprotinin-human-fibrinogen-and-calcium-chloride-dihydrate-in-patients-undergoing-total-gastrectomy/ Wed, 29 Apr 2026 15:03:12 +0000 https://clinicaltrials.eu/trial/study-on-fibrin-adhesive-to-prevent-leaks-after-stomach-cancer-surgery-using-aprotinin-human-fibrinogen-and-calcium-chloride-dihydrate-in-patients-undergoing-total-gastrectomy/ This clinical trial is focused on studying a condition called esophagojejunal anastomosis dehiscence, which can occur after a surgery known as total gastrectomy for treating gastric cancer. This condition involves a leak at the surgical connection between the esophagus and the small intestine. The study is testing a treatment called TISSEEL, a fibrin-based adhesive, which is used to help seal tissues during surgery. TISSEEL contains several substances, including aprotinin, human fibrinogen, calcium chloride dihydrate, human thrombin, and human coagulation factor XIII.

The purpose of the study is to see if using TISSEEL can reduce the chances of developing esophagojejunal anastomosis dehiscence after surgery. Participants in the study will undergo surgery as part of their treatment for gastric cancer. During the surgery, TISSEEL will be applied to help prevent leaks at the surgical site. The study will monitor participants for any signs of leaks or other complications in the days following the surgery.

The study will last for a period of time, with participants being observed for any complications or the need for additional surgery. The goal is to determine if TISSEEL is effective in reducing the risk of leaks and improving recovery after surgery for gastric cancer. Participants will be monitored closely to ensure their safety and to gather information on the effectiveness of the treatment.

]]> Study on the Effects of Amylase, Protease, and Rizolipase for Patients After Gastrectomy https://clinicaltrials.eu/trial/study-on-the-effects-of-amylase-protease-and-rizolipase-for-patients-after-gastrectomy/ Wed, 29 Apr 2026 14:24:31 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-amylase-protease-and-rizolipase-for-patients-after-gastrectomy/ This clinical trial is focused on patients who have undergone a gastrectomy, which is a surgical procedure to remove part or all of the stomach. The study is investigating whether taking a medication called Nortase® with every meal can improve the quality of life for these patients six months after their surgery. Nortase® is a medication that contains enzymes such as amylase, protease, and rizolipase, which help in digesting food.

The purpose of the study is to determine if enzyme supplementation can lead to better disease-specific quality of life for patients after a gastrectomy. Participants in the study will be randomly assigned to receive either Nortase® or a placebo, which is a substance with no active medication. The study will last for six months, during which participants will take the assigned capsules with their meals.

Throughout the study, participants will be monitored to assess their quality of life, focusing on physical well-being. The goal is to see if those taking Nortase® experience improvements compared to those taking the placebo. This research aims to provide valuable insights into the potential benefits of enzyme supplementation for individuals recovering from gastrectomy.

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