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	<title>Enuresis &#8211; European Clinical Trials Information Network</title>
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	<title>Enuresis &#8211; European Clinical Trials Information Network</title>
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		<title>Study on Daridorexant for Treating Bedwetting in Adolescents</title>
		<link>https://clinicaltrials.eu/trial/study-on-daridorexant-for-treating-bedwetting-in-adolescents/</link>
		
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		<pubDate>Wed, 29 Apr 2026 15:06:19 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-daridorexant-for-treating-bedwetting-in-adolescents/</guid>

					<description><![CDATA[This study examines the effectiveness of daridorexant in treating adolescents with nocturnal enuresis, a condition characterized by involuntary urination during sleep (bedwetting) that occurs at least three times per week. The research will test if this medication can help reduce the frequency of bedwetting episodes in teenagers aged 15-17 who have not responded to standard [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study examines the effectiveness of <b>daridorexant</b> in treating adolescents with <b>nocturnal enuresis</b>, a condition characterized by involuntary urination during sleep (bedwetting) that occurs at least three times per week. The research will test if this medication can help reduce the frequency of bedwetting episodes in teenagers aged 15-17 who have not responded to standard treatments like alarm systems or <b>desmopressin</b>.</p>
<p>The investigation is designed as a <b>randomized, double-blind, placebo-controlled study</b>, which means some participants will receive the actual medication while others will receive a placebo, with neither the participants nor the researchers knowing who receives which treatment during the study. Researchers will monitor changes in the number of wet nights per week, measure the amount of urine produced at night, assess <b>bladder capacity</b>, and track any side effects that may occur.</p>
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		<title>Study Comparing Desmopressin and Desmopressin Acetate in Children with Bedwetting (Nocturnal Enuresis)</title>
		<link>https://clinicaltrials.eu/trial/study-comparing-desmopressin-and-desmopressin-acetate-in-children-with-bedwetting-nocturnal-enuresis/</link>
		
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		<pubDate>Wed, 29 Apr 2026 15:05:57 +0000</pubDate>
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					<description><![CDATA[This clinical trial is focused on studying a condition known as nocturnal enuresis, which is more commonly referred to as bedwetting. The study involves children who experience this condition. The trial will compare two different treatments that contain the active ingredient desmopressin. The two treatments being compared are called Minirin and Desmopressin &#8220;Sandoz&#8221;. Both of [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying a condition known as <i>nocturnal enuresis</i>, which is more commonly referred to as bedwetting. The study involves children who experience this condition. The trial will compare two different treatments that contain the active ingredient <i>desmopressin</i>. The two treatments being compared are called <i>Minirin</i> and <i>Desmopressin &#8220;Sandoz&#8221;</i>. Both of these treatments are designed to help manage bedwetting by affecting how the body concentrates urine.</p>
<p>The purpose of the study is to understand the differences in how these two forms of desmopressin work in the body. This includes looking at how the body absorbs and processes the medication, as well as how effective each treatment is at concentrating urine. The study will involve children taking one of the two medications, and their responses will be monitored over a period of time. The children will take the medication either as an <i>oral lyophilisate</i>, which is a type of tablet that dissolves in the mouth, or as a <i>sublingual tablet</i>, which is placed under the tongue to dissolve.</p>
<p>Throughout the study, researchers will collect information on how the medications affect urine concentration and output. They will also gather feedback on the taste and texture of the medications to understand which one is preferred by the participants. The study aims to provide valuable insights into the best treatment options for children with bedwetting, helping to improve their quality of life.</p>
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