Elderly – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:30:49 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Elderly – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Early Sedation with Dexmedetomidine vs. Placebo for Older Critically Ill Patients on Ventilators https://clinicaltrials.eu/trial/study-on-early-sedation-with-dexmedetomidine-vs-placebo-for-older-critically-ill-patients-on-ventilators/ Wed, 29 Apr 2026 14:26:40 +0000 https://clinicaltrials.eu/trial/study-on-early-sedation-with-dexmedetomidine-vs-placebo-for-older-critically-ill-patients-on-ventilators/ This clinical trial is focused on studying the effects of early sedation in older patients who are critically ill and require intensive medical care, including the use of machines to help them breathe, known as mechanical ventilation. The study involves patients who are 65 years or older and are in need of continuous sedative medication to ensure comfort and safety while receiving life-supporting treatments. The medication being tested is called Dexmedetomidine, which is given as a solution through an infusion. This trial compares the effects of Dexmedetomidine with a placebo, which is a substance with no active medication, to see if it can improve outcomes for these patients.

The main goal of the study is to evaluate the impact of using Dexmedetomidine as a primary sedative on the survival of patients over a period of 90 days. The study will also look at other important factors, such as the number of days patients are alive without experiencing coma or delirium, the number of days they are free from the ventilator, and any major kidney problems that may occur. Additionally, the study will assess how long patients need mechanical ventilation and their length of stay in the hospital.

The trial is expected to run until December 2025, with the recruitment of participants having started in August 2023. The findings from this study could help improve the care and treatment of older patients who are critically ill and require mechanical ventilation.

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