Diverticulitis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 17 Jun 2026 04:02:59 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Diverticulitis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Outpatient Treatment Without Antibiotics or with Ciprofloxacin, Cefuroxime, Cefditoren Pivoxil, Amoxicillin/Clavulanic Acid, and Metronidazole in Adults with Acute Uncomplicated Diverticulitis https://clinicaltrials.eu/trial/a-study-to-compare-treatment-without-antibiotics-versus-a-drug-combination-of-cefditoren-pivoxil-ciprofloxacin-cefuroxime-metronidazole-and-amoxicillin-and-clavulanic-acid-in-patients-with-acute-uncom/ Thu, 07 May 2026 05:47:13 +0000 https://clinicaltrials.eu/trial/a-study-to-compare-treatment-without-antibiotics-versus-a-drug-combination-of-cefditoren-pivoxil-ciprofloxacin-cefuroxime-metronidazole-and-amoxicillin-and-clavulanic-acid-in-patients-with-acute-uncom/ This clinical trial is studying acute uncomplicated diverticulitis, a condition in which small pouches in the bowel become inflamed, without signs of a more serious infection. The purpose of the study is to compare outpatient treatment without antibiotics with outpatient treatment using antibiotics.

The treatments being studied are oral tablets of metronidazole, amoxicillin/clavulanic acid, cefditoren pivoxil, ciprofloxacin, and cefuroxime. These are medicines taken by mouth that are commonly used to treat bacterial infections. The study looks at whether people can be treated safely without antibiotics or whether antibiotic treatment works better in this condition.

People in the study receive outpatient care, meaning treatment without staying in the hospital. The course of the study includes starting treatment and then follow-up over time to see how the condition improves or returns. The study also checks for any later episodes of diverticulitis and how quickly normal daily activities are resumed. The trial is being carried out at several centers.

]]> Study on MBK-01 and Drug Combination for Treating Patients with Recurrent Diverticulitis https://clinicaltrials.eu/trial/study-on-mbk-01-and-drug-combination-for-treating-patients-with-recurrent-diverticulitis/ Wed, 29 Apr 2026 14:25:29 +0000 https://clinicaltrials.eu/trial/study-on-mbk-01-and-drug-combination-for-treating-patients-with-recurrent-diverticulitis/ This clinical trial is focused on studying the treatment of recurring diverticulitis, a condition where small, bulging pouches in the digestive tract become inflamed or infected repeatedly. The trial will use an investigational treatment called MBK-01, which consists of lyophilized capsules of fecal microbiota. These capsules are designed to help restore the natural balance of bacteria in the intestines. The study will also involve the use of other medications, including metronidazole, fosfomycin, and amoxicillin, which are commonly used antibiotics.

The purpose of the study is to evaluate how effective and safe the MBK-01 treatment is in reducing the frequency of acute diverticulitis episodes. Participants will be randomly assigned to receive either the MBK-01 treatment or a control treatment. The study will monitor the number of new episodes of acute diverticulitis, any side effects, and changes in health indicators throughout the trial. The trial will also help determine the best dosage of MBK-01 for treating this condition.

Participants will take the treatment orally, and the study will last for a period of time during which they will be regularly monitored by healthcare professionals. The trial aims to provide valuable information on how well MBK-01 works in managing recurring diverticulitis and its potential benefits for patients suffering from this condition.

]]>