Dental local anaesthesia – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:28:15 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Dental local anaesthesia – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Pain Relief for Dental Procedures in Patients with MC1R Mutation Using Lidocaine-Prilocaine Combination and Lidocaine Alone https://clinicaltrials.eu/trial/study-on-pain-relief-for-dental-procedures-in-patients-with-mc1r-mutation-using-lidocaine-prilocaine-combination-and-lidocaine-alone/ Wed, 29 Apr 2026 15:05:35 +0000 https://clinicaltrials.eu/trial/study-on-pain-relief-for-dental-procedures-in-patients-with-mc1r-mutation-using-lidocaine-prilocaine-combination-and-lidocaine-alone/ This clinical trial is focused on dental procedures that require local anesthesia. The study is investigating the effectiveness of two different anesthetic solutions. One solution is a combination of lidocaine and prilocaine, while the other contains only lidocaine. These medications are used to numb the area in the mouth where dental work is being performed, helping to reduce pain during the procedure.

The purpose of the study is to compare how well these two anesthetic solutions work in people who have a specific genetic trait known as the MC1R mutation. This mutation is often associated with red hair. Participants in the study will receive either the lidocaine-prilocaine combination or the lidocaine alone, and the effectiveness of the anesthesia will be assessed during their dental treatment.

Throughout the study, participants will undergo dental procedures where the anesthetic solutions will be used. The study will measure how well the anesthesia works by checking if the participants feel any sensation in the treated area. The study will also gather feedback from participants about their experience with the anesthesia. This research aims to provide valuable information on the best anesthetic options for dental procedures in individuals with the MC1R mutation.

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