Delirium tremens – European Clinical Trials Information Network

Comparison of Oxazepam 50 mg orodispersible tablets and Oxazepam 50 mg standard tablets in healthy volunteers to test if they work the same way in the body

Wed, 29 Apr 2026 15:07:14 +0000

This clinical trial compares two forms of oxazepam, a medication belonging to the benzodiazepine group of drugs. The study evaluates how the body processes a new orodispersible tablet form (dissolves in the mouth) compared to the standard tablet form of oxazepam. One medication is called Oxazepam 50 mg orodispersible tablets, and the other is Seresta 50 mg tablets.

The purpose of this study is to determine if both forms of the medication work similarly in the body. The study uses a crossover design, which means participants will receive both forms of the medication at different times. Both medications contain the same active ingredient and the same strength of 50 mg.

During the study, healthy participants will take a single dose of each medication form. Blood samples will be collected to measure how much of the medication enters the bloodstream and how long it stays in the body. The study also looks at how well participants tolerate the orodispersible tablet and monitors for any side effects. This is not a treatment study for any specific medical condition but rather a comparison of two different forms of the same medication.

Study on the Bioequivalence of Oxazepam 10 mg Orodispersible Tablets Compared to Standard Tablets in Healthy Volunteers

Wed, 29 Apr 2026 15:05:51 +0000

This clinical trial is focused on comparing two forms of the medication Oxazepam, which is commonly used to treat anxiety. The study involves Oxazepam 10 mg orodispersible tablets and Seresta 10 mg tablets. The purpose of the study is to compare how the body absorbs these two forms of the medication and to determine if they are equivalent in terms of their effects.

The study is designed as a single-dose, open-label trial, meaning that participants will know which form of the medication they are taking. It involves healthy individuals who will receive both forms of the medication at different times. Participants will take the medication orally, and the study will observe how the body processes each form. The trial will also assess the safety of the medications by monitoring any side effects and checking vital signs, such as heart rate and blood pressure.

Additionally, the study will evaluate the taste and ease of use of the orodispersible tablet form. This involves placing the tablet on the tongue and assessing its palatability shortly after. The trial aims to provide valuable information on whether the two forms of Oxazepam are interchangeable, which could help inform future treatment options for patients requiring this medication.