Coronary artery occlusion – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:15:18 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Coronary artery occlusion – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Theophylline, Gadoteric Acid, and Regadenoson for Patients with Chronic Total Coronary Artery Blockage https://clinicaltrials.eu/trial/study-on-theophylline-gadoteric-acid-and-regadenoson-for-patients-with-chronic-total-coronary-artery-blockage/ Wed, 29 Apr 2026 15:04:03 +0000 https://clinicaltrials.eu/trial/study-on-theophylline-gadoteric-acid-and-regadenoson-for-patients-with-chronic-total-coronary-artery-blockage/ This clinical trial is focused on studying patients with coronary artery chronic total occlusion, a condition where a coronary artery is completely blocked for a long period. The study aims to evaluate the effectiveness of different imaging techniques in detecting heart muscle health and blood flow issues in these patients. The imaging methods being used include coronary CT angiography, myocardial perfusion imaging, and stress cardiac MRI. These techniques help doctors see how well blood is flowing to the heart and if there are any areas of the heart muscle that are not getting enough blood.

During the study, participants will receive injections of different substances to help with imaging. These include theophylline anhydrous, which is used to help open up the airways in the lungs, gadoteric acid, a contrast agent that helps make blood vessels and tissues more visible on MRI scans, and regadenoson, a medication that helps to widen the blood vessels of the heart. The study will compare the results of these imaging techniques to see how well they can detect areas of the heart that are not getting enough blood or have been damaged.

The purpose of this study is to improve the understanding of how these imaging techniques can be used to assess heart health in patients with chronic total occlusion. Participants will undergo these imaging tests at the beginning of the study and again after six months. The study will also monitor for any side effects or adverse events that may occur during the imaging procedures. This research aims to provide valuable information that could help improve the diagnosis and treatment of patients with this heart condition in the future.

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