Chorioretinitis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:14:04 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Chorioretinitis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Effects of Brepocitinib and Prednisone for Adults with Active Non-Infectious Uveitis https://clinicaltrials.eu/trial/study-on-the-effects-of-brepocitinib-and-prednisone-for-adults-with-active-non-infectious-uveitis/ Wed, 29 Apr 2026 15:02:39 +0000 https://clinicaltrials.eu/trial/study-on-the-effects-of-brepocitinib-and-prednisone-for-adults-with-active-non-infectious-uveitis/ This clinical trial is focused on studying a condition called non-infectious uveitis, which is an inflammation inside the eye that is not caused by an infection. The study specifically looks at three types of this condition: intermediate uveitis, posterior uveitis, and panuveitis. The main treatment being tested in this study is a medication called brepocitinib, which is taken orally in the form of a tablet. The study also involves the use of a placebo tablet, which looks like the brepocitinib tablet but does not contain the active medication.

The purpose of the study is to evaluate how effective brepocitinib is in treating the inflammation associated with non-infectious uveitis. Participants in the study will be randomly assigned to receive either brepocitinib or a placebo. The study will last for a period of up to 96 weeks, during which participants will take the medication and attend regular check-ups to monitor their condition and any changes in their symptoms.

Throughout the study, doctors will closely observe the participants to see how well the treatment works and to ensure their safety. The study aims to provide valuable information on whether brepocitinib can help reduce the inflammation and improve the symptoms of non-infectious uveitis. This research could potentially lead to better treatment options for people living with this eye condition.

]]> Study on Izokibep for Patients with Non-infectious Uveitis https://clinicaltrials.eu/trial/study-on-izokibep-for-patients-with-non-infectious-uveitis/ Wed, 29 Apr 2026 15:00:30 +0000 https://clinicaltrials.eu/trial/study-on-izokibep-for-patients-with-non-infectious-uveitis/ This clinical trial is focused on studying a condition called non-infectious uveitis, which affects the middle, back, or entire eye. Uveitis is an inflammation of the eye that can cause redness, pain, and vision problems. The study is testing a new treatment called Izokibep, which is given as an injection under the skin. Izokibep is being compared to a placebo to see how well it works in treating this eye condition.

The purpose of the study is to evaluate the effectiveness and safety of Izokibep in people with non-infectious uveitis. Participants in the study will receive either Izokibep or a placebo and will be monitored over a period of time to see how their condition responds to the treatment. The study will last for up to 52 weeks, with regular check-ups to assess the health of the participants’ eyes and overall well-being.

Throughout the study, participants will be closely observed to track any changes in their condition and to ensure their safety. The main goal is to determine if Izokibep can help reduce the symptoms of uveitis and improve the quality of life for those affected by this condition. This research could lead to new treatment options for people living with non-infectious uveitis.

]]> Study on the Safety and Effectiveness of Fluocinolone Acetonide Implant for Children Aged 6-17 with Recurrent Non-Infectious Uveitis in the Eye’s Posterior Segment https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-fluocinolone-acetonide-implant-for-children-aged-6-17-with-recurrent-non-infectious-uveitis-in-the-eyes-posterior-segment/ Wed, 29 Apr 2026 14:28:02 +0000 https://clinicaltrials.eu/trial/study-on-the-safety-and-effectiveness-of-fluocinolone-acetonide-implant-for-children-aged-6-17-with-recurrent-non-infectious-uveitis-in-the-eyes-posterior-segment/ This clinical trial is focused on studying a condition called non-infectious uveitis, which affects the back part of the eye. This condition can cause inflammation and swelling, leading to vision problems. The study is testing a treatment called ILUVIEN, which is an implant placed inside the eye. The implant contains a small amount of a medication called fluocinolone acetonide, which is designed to help reduce inflammation over a long period.

The purpose of the study is to evaluate the safety and effectiveness of the ILUVIEN implant in children aged 6 to less than 18 years who have recurrent non-infectious uveitis. Participants in the study will receive the implant and be monitored over a period of time to see how well the treatment works and to check for any side effects. The study will look at various outcomes, such as the reduction of swelling in the eye, changes in vision, and the rate of recurrence of the uveitis.

Throughout the study, participants will have regular check-ups to assess their eye health and the effectiveness of the treatment. The study aims to provide valuable information on how well the ILUVIEN implant works in managing non-infectious uveitis in children and to ensure that it is safe for use in this age group. Participants will be closely monitored by healthcare professionals to ensure their safety and well-being during the trial.

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