Cholelithiasis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 05 Jun 2026 10:55:37 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Cholelithiasis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A study to evaluate if atorvastatin prevents gallstones in patients undergoing bariatric surgery https://clinicaltrials.eu/trial/a-study-to-evaluate-if-atorvastatin-prevents-gallstones-in-patients-undergoing-bariatric-surgery/ Wed, 27 May 2026 04:05:18 +0000 https://clinicaltrials.eu/trial/a-study-to-evaluate-if-atorvastatin-prevents-gallstones-in-patients-undergoing-bariatric-surgery/ This study focuses on the prevention of gallstones, which are hard deposits that can form in the gallbladder, in people who have undergone bariatric surgery, a procedure used for significant weight loss. The purpose of the study is to evaluate whether the medication atorvastatin can help prevent these stones from forming. This medication is an oral drug used to lower cholesterol, a fatty substance found in the blood.

Participants in the study will receive either atorvastatin or standard care. If atorvastatin is used, it is taken once daily, starting two weeks before the surgery and continuing for six months afterward. The study will monitor changes in LDL-cholesterol, which is often referred to as bad cholesterol, as well as levels of bile acids, which are substances produced by the liver to help digest fats. The process includes monitoring for any side effects related to the medication during the period following the surgery.

]]> Study comparing low and standard doses of Indocyanine Green for fluorescence imaging during gallbladder removal surgery in patients with gallstones https://clinicaltrials.eu/trial/comparing-low-dose-versus-standard-dose-of-indocyanine-green-for-fluorescence-imaging-during-gallbladder-removal-surgery-in-patients-with-gallstones/ Wed, 29 Apr 2026 15:06:20 +0000 https://clinicaltrials.eu/trial/comparing-low-dose-versus-standard-dose-of-indocyanine-green-for-fluorescence-imaging-during-gallbladder-removal-surgery-in-patients-with-gallstones/ This study focuses on patients with symptomatic cholelithiasis, a condition where gallstones cause symptoms such as pain and discomfort. The study examines different approaches during laparoscopic cholecystectomy, which is a minimally invasive surgery to remove the gallbladder. The research uses indocyanine green, a special dye that helps surgeons see the bile ducts more clearly during the operation.

The study compares two different ways of using the dye during surgery. One group of patients receives a standard dose of the dye several hours before surgery, while the other group receives a smaller dose just before the operation. The purpose is to determine which method provides better visualization of the bile ducts during the surgical procedure.

During the operation, doctors use a special camera system that can detect the dye, making certain parts of the body’s structures glow and become more visible. This helps them see important structures more clearly during the surgery. The study will evaluate how well doctors can see these structures and how helpful the technique is during the operation.

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