Cholecystitis acute – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:15:34 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Cholecystitis acute – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Preoperative Antibiotics for Patients with Acute Cholecystitis: Comparing Ertapenem, Ciprofloxacin, and Cefuroxime https://clinicaltrials.eu/trial/study-on-preoperative-antibiotics-for-patients-with-acute-cholecystitis-comparing-ertapenem-ciprofloxacin-and-cefuroxime/ Wed, 29 Apr 2026 15:04:23 +0000 https://clinicaltrials.eu/trial/study-on-preoperative-antibiotics-for-patients-with-acute-cholecystitis-comparing-ertapenem-ciprofloxacin-and-cefuroxime/ This clinical trial is focused on studying the effects of antibiotics in patients with acute cholecystitis, which is an inflammation of the gallbladder. The study will compare the outcomes of using a single dose of antibiotics versus continuous antibiotic treatment before surgery. The antibiotics being tested include ertapenem (marketed as INVANZ), ciprofloxacin (marketed as Ciprofloxacin Fresenius Kabi), and cefuroxime (marketed as Cefuroxime Orion Pharma). These medications are administered intravenously, meaning they are given directly into a vein.

The purpose of the study is to determine which antibiotic approach is more effective in reducing the risk of infections after surgery in patients undergoing gallbladder removal due to acute cholecystitis. Participants in the study will be randomly assigned to receive either a single dose or continuous doses of antibiotics before their surgery. The study will monitor the rate of infections and other complications within 30 days after the surgery.

By participating in this study, researchers aim to gather valuable information that could improve treatment strategies for patients with acute cholecystitis. The study will also look at other factors such as the need to switch from a less invasive surgery to a more invasive one, the overall complication rate, and any side effects related to the antibiotics used. The findings from this study could help in making informed decisions about the best preoperative antibiotic treatment for patients with this condition.

]]> Study on Indocyanine Green for Patients Undergoing Emergency Surgery for Acute Cholecystitis https://clinicaltrials.eu/trial/study-on-indocyanine-green-for-patients-undergoing-emergency-surgery-for-acute-cholecystitis/ Wed, 29 Apr 2026 14:58:20 +0000 https://clinicaltrials.eu/trial/study-on-indocyanine-green-for-patients-undergoing-emergency-surgery-for-acute-cholecystitis/ This clinical trial is focused on studying the use of indocyanine green in patients with acute cholecystitis, a condition where the gallbladder becomes inflamed, often requiring urgent surgery known as a cholecystectomy. The trial aims to determine if using indocyanine green can help reduce the time needed for this surgery. Indocyanine green is a substance that, when injected, can help surgeons see the bile ducts more clearly during the operation, potentially reducing the risk of injury.

The study involves patients who need an urgent laparoscopic cholecystectomy, which is a minimally invasive surgery to remove the gallbladder. Participants will receive indocyanine green before the surgery. The main goal is to see if this approach can shorten the surgical time by at least 10 minutes compared to the traditional method. This could make the procedure safer and more efficient.

During the trial, participants will undergo the surgery with the use of indocyanine green, and the time taken from the first incision to the closure of the skin will be recorded. The study is designed to provide valuable insights into improving surgical outcomes for patients with acute cholecystitis.

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