Cholecystectomy – European Clinical Trials Information Network

Efficacy of sufentanil versus fentanyl for postoperative pain in patients undergoing urgent laparoscopic cholecystectomy

Wed, 17 Jun 2026 04:03:08 +0000

The study focuses on patients who need an urgent laparoscopic cholecystectomy, a short operation that removes the gallbladder through a few small cuts. During the operation, the pain‑relieving medicine sufentanil will be given through an intravenous (into a vein) line using a steady, computer‑controlled flow, and its effectiveness will be compared with the standard opioid fentanyl that is normally used for this type of surgery. The purpose of the study is to determine whether the new method provides pain control that is not worse than the usual treatment.

Participants will receive one of the two medicines while they are under anesthesia for the surgery. After the operation, they will stay in the recovery area and be asked to rate their pain at several times during the first day. Pain will be measured with the Visual Analogue Scale, a simple line where patients mark how strong their pain feels, from “no pain” to “worst pain imaginable.” Researchers will also watch for common side effects such as nausea, itching, or breathing problems.

The follow‑up period lasts about 24 hours, during which the amount of additional pain medication needed and any unwanted reactions will be recorded. At the end of the study, the collected information will help decide if the new medication method can be used as an alternative to the current standard for managing pain after this surgery.

Study on Esmolol Hydrochloride vs. Sufentanil Citrate for Recovery Quality in Patients Undergoing Laparoscopic Gallbladder Surgery with Anesthesia

Wed, 29 Apr 2026 15:04:58 +0000

This clinical trial is focused on patients undergoing a procedure called laparoscopic cholecystectomy, which is a minimally invasive surgery to remove the gallbladder. The study aims to compare two medications, Esmolol and Sufentanil, to see which one provides better comfort and recovery quality after the surgery. Both medications are given as injections during anesthesia, which is the process of using medicine to prevent pain during surgery. Esmolol is often used to manage heart rate and blood pressure, while Sufentanil is a strong pain reliever.

The purpose of the study is to evaluate whether using Esmolol is as effective as using Sufentanil for improving patient comfort after surgery. Participants will be randomly assigned to receive either Esmolol or Sufentanil during their anesthesia. After the surgery, the quality of recovery will be assessed using a questionnaire the day after the procedure. The study will also monitor other factors such as pain levels, any sore throat, changes in blood pressure, heart rate, and the need for additional medications during the operation.

The trial is designed to ensure that the recovery process is as comfortable as possible for patients undergoing this type of surgery. By comparing these two medications, the study aims to find the best approach to enhance recovery and overall patient experience after a laparoscopic cholecystectomy.