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	<title>Cataract &#8211; European Clinical Trials Information Network</title>
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	<title>Cataract &#8211; European Clinical Trials Information Network</title>
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		<title>Study of herbal medicine combination and bromazepam for anxiety and pain in patients having eye surgery with retrobulbar anesthesia</title>
		<link>https://clinicaltrials.eu/trial/study-of-herbal-medicine-combination-and-bromazepam-for-anxiety-and-pain-in-patients-having-eye-surgery-with-retrobulbar-anesthesia/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Thu, 30 Apr 2026 13:08:22 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-of-herbal-medicine-combination-and-bromazepam-for-anxiety-and-pain-in-patients-having-eye-surgery-with-retrobulbar-anesthesia/</guid>

					<description><![CDATA[This study examines patients who are having eye surgery, specifically vitrectomy or cataract surgery. Vitrectomy is a procedure where the gel-like substance inside the eye is removed, while cataract surgery involves removing the cloudy lens of the eye and replacing it with a clear artificial one. These surgeries require a type of numbing injection called [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study examines patients who are having eye surgery, specifically <b>vitrectomy</b> or <b>cataract surgery</b>. Vitrectomy is a procedure where the gel-like substance inside the eye is removed, while cataract surgery involves removing the cloudy lens of the eye and replacing it with a clear artificial one. These surgeries require a type of numbing injection called <b>retrobulbar anaesthesia</b>, which is given behind the eyeball to block pain during the operation. The study will use two different treatments: one is a herbal medicine tablet called <b>Nervenruh forte</b> that contains plant extracts from hops flower, valerian root, and passionflower, and the other is a medication called <b>Bromazepam</b>. Both of these medications are intended to help reduce anxiety and discomfort. The purpose of the study is to investigate whether listening to music and taking herbal medicine can reduce pain and anxiety during the time around the surgery.</p>
<p>During the study, patients will receive one of the treatments before their eye surgery. The study will measure pain and anxiety levels at different times: when patients first arrive, before the numbing injection is given, right after the injection is given, and immediately after the surgery is completed. Pain will be measured using a scale where patients rate their pain level, and anxiety will be measured using questionnaires that ask about feelings of nervousness or worry. The study will also record how long it takes to give the numbing injection behind the eye.</p>
<p>Patients participating in this study will be adults over 18 years old who need surgery on one eye only. The treatments being tested are taken by mouth in tablet form. The study aims to understand whether these approaches can make the surgical experience less painful and less stressful for patients undergoing this type of eye surgery with retrobulbar anaesthesia.</p>
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		<title>Comparing the effectiveness of nepafenac and dexamethasone sodium phosphate for treating eye inflammation after cataract surgery</title>
		<link>https://clinicaltrials.eu/trial/comparing-the-effectiveness-of-nepafenac-and-dexamethasone-sodium-phosphate-for-treating-eye-inflammation-after-cataract-surgery/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 15:09:11 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/comparing-the-effectiveness-of-nepafenac-and-dexamethasone-sodium-phosphate-for-treating-eye-inflammation-after-cataract-surgery/</guid>

					<description><![CDATA[This study focuses on Postoperative inflammation after cataract surgery, which is redness, swelling, or irritation in the eye that can occur after an operation to remove a cloudy lens. The goal of the study is to compare a combination of two medications in one dropper against using each medication separately to see which helps reduce [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on <b>Postoperative inflammation after cataract surgery</b>, which is redness, swelling, or irritation in the eye that can occur after an operation to remove a cloudy lens. The goal of the study is to compare a combination of two medications in one dropper against using each medication separately to see which helps reduce eye inflammation more quickly. The medications being studied include a combination of <b>dexamethasone sodium phosphate</b> and <b>nepafenac</b>, while the individual components used for comparison are <b>nepafenac</b> and <b>dexamethasone phosphate</b>. Additionally, <b>tobramycin</b> may be used as a background treatment.</p>
<p>During the study, participants will use different types of eye drops. The research will monitor several aspects of eye health, such as <b>conjunctival hyperaemia</b>, which is an increase in blood flow that makes the white part of the eye look red, and <b>ocular pain</b> or discomfort. The study also looks at <b>central macular thickness</b>, which refers to the thickness of the part of the retina responsible for sharp, central vision, using a specialized imaging method called <b>optical coherence tomography</b>. Other factors monitored include <b>intraocular pressure</b>, which is the fluid pressure inside the eye, and <b>best corrected visual acuity</b>, which is the clearest vision possible with the help of glasses or contact lenses.</p>
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		<title>Study on Reducing Inflammation After Cataract Surgery Using Nepafenac and Dexamethasone for Patients Undergoing Surgery</title>
		<link>https://clinicaltrials.eu/trial/study-on-reducing-inflammation-after-cataract-surgery-using-nepafenac-and-dexamethasone-for-patients-undergoing-surgery/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:58:47 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-reducing-inflammation-after-cataract-surgery-using-nepafenac-and-dexamethasone-for-patients-undergoing-surgery/</guid>

					<description><![CDATA[This clinical trial is focused on studying the effects of medications used in patients undergoing surgery for cataracts, which is a condition where the lens of the eye becomes cloudy, leading to vision problems. The study will explore how different medication regimens can affect inflammation inside the eye after surgery. Inflammation is the body&#8217;s response [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the effects of medications used in patients undergoing surgery for <b>cataracts</b>, which is a condition where the lens of the eye becomes cloudy, leading to vision problems. The study will explore how different medication regimens can affect inflammation inside the eye after surgery. Inflammation is the body&#8217;s response to injury or irritation, and in this case, it occurs in the eye following the surgical procedure.</p>
<p>The medications being studied include <b>NEVANAC</b> (nepafenac) and <b>Spersadex</b> (dexamethasone), both of which are administered as eye drops. NEVANAC is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce inflammation and pain, while Spersadex is a corticosteroid that also helps in reducing inflammation. The study will compare the effects of these medications on postoperative inflammation to determine the best approach for managing inflammation after cataract surgery.</p>
<p>Participants in the study will receive one of the medication regimens before their cataract surgery. The study will monitor the level of inflammation in the eye after the surgery to assess the effectiveness of the medications. The goal is to find the most effective way to manage inflammation, which can help improve recovery and outcomes for patients undergoing cataract surgery.</p>
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		<title>Comparison of preservative-free versus preserved dexamethasone and diclofenac eye drops in patients after cataract surgery</title>
		<link>https://clinicaltrials.eu/trial/study-comparing-preservative-free-dexamethasone-and-diclofenac-eye-drops-with-preserved-versions-for-patients-after-cataract-surgery/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:58:08 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-comparing-preservative-free-dexamethasone-and-diclofenac-eye-drops-with-preserved-versions-for-patients-after-cataract-surgery/</guid>

					<description><![CDATA[This study focuses on treating patients who have undergone cataract surgery. A cataract is a condition where the natural lens of the eye becomes cloudy, making it difficult to see clearly. The study compares two different types of eye drop treatments &#8211; one group contains preservatives while the other is preservative-free. The medications being tested [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on treating patients who have undergone <b>cataract surgery</b>. A cataract is a condition where the natural lens of the eye becomes cloudy, making it difficult to see clearly. The study compares two different types of eye drop treatments &#8211; one group contains preservatives while the other is preservative-free. The medications being tested are <b>dexamethasone</b> (Monofree Dexamethason and Maxidex) and <b>diclofenac</b> (Dicloabak and Voltaren Ophtha) eye drops.</p>
<p>The purpose of this research is to determine if preservative-free eye drops work better than preserved eye drops after cataract surgery. During the study, participants receive either preservative-free or preserved eye drops for their post-surgery treatment. The treatment continues for 4 weeks after the cataract surgery.</p>
<p>Both types of eye drops contain the same active medicines &#8211; dexamethasone, which reduces inflammation, and diclofenac, which helps manage pain and inflammation. The only difference between the two treatment groups is that one contains preservatives while the other does not. The study measures various aspects of eye health, including tear production, eye surface condition, and inflammation levels.</p>
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		<title>Study on the Effect and Safety of Phenylephrine Hydrochloride, Tropicamide, and Lidocaine Hydrochloride in Children with Cataracts Undergoing Surgery</title>
		<link>https://clinicaltrials.eu/trial/study-on-the-effect-and-safety-of-phenylephrine-hydrochloride-tropicamide-and-lidocaine-hydrochloride-in-children-with-cataracts-undergoing-surgery/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:24:00 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-the-effect-and-safety-of-phenylephrine-hydrochloride-tropicamide-and-lidocaine-hydrochloride-in-children-with-cataracts-undergoing-surgery/</guid>

					<description><![CDATA[This clinical trial is focused on studying the effects and safety of a medication called Mydrane in children who are undergoing surgery for pediatric cataract. A cataract is a condition where the lens of the eye becomes cloudy, leading to vision problems. The treatment involves an injection of Mydrane directly into the eye during the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on studying the effects and safety of a medication called <i>Mydrane</i> in children who are undergoing surgery for <i>pediatric cataract</i>. A cataract is a condition where the lens of the eye becomes cloudy, leading to vision problems. The treatment involves an injection of Mydrane directly into the eye during the surgery. Mydrane is a combination of three substances: <i>phenylephrine hydrochloride</i>, <i>tropicamide</i>, and <i>lidocaine hydrochloride</i>. These substances work together to help dilate the pupil, which is the opening in the center of the eye, and to provide local anesthesia, which numbs the area to prevent pain during the procedure.</p>
<p>The purpose of this study is to evaluate how effective and safe Mydrane is when used in children. During the study, children who are scheduled for cataract surgery will receive an injection of Mydrane. The study will monitor how well the pupil dilates, which is important for the surgery to be performed without needing additional mechanical dilation. Additionally, the study will observe any changes in heart rate and blood pressure to ensure the safety of the medication.</p>
<p>Participants in the study will be children aged 8 weeks to 17 years who are undergoing cataract surgery. The study aims to provide valuable information on the use of Mydrane in pediatric patients, helping to improve surgical outcomes and ensure the safety of young patients undergoing this procedure.</p>
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