Cancer surgery – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:16:14 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Cancer surgery – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Reducing Morphine Use After Throat and Neck Cancer Surgery Using Ropivacaine and Sodium Chloride for Patients Undergoing Cancer Surgery https://clinicaltrials.eu/trial/study-on-reducing-morphine-use-after-throat-and-neck-cancer-surgery-using-ropivacaine-and-sodium-chloride-for-patients-undergoing-cancer-surgery/ Wed, 29 Apr 2026 15:05:04 +0000 https://clinicaltrials.eu/trial/study-on-reducing-morphine-use-after-throat-and-neck-cancer-surgery-using-ropivacaine-and-sodium-chloride-for-patients-undergoing-cancer-surgery/ This clinical trial is focused on patients undergoing surgery for throat and neck cancer. The study aims to evaluate a specific anesthesia technique called the superficial cervical plexus block. This technique is used to reduce the amount of morphine, a pain medication, needed after surgery. The trial involves the use of two medications: sodium chloride, which is a common salt solution used in medical settings, and ropivacaine, a local anesthetic that numbs a specific area of the body.

The purpose of the study is to see if this anesthesia technique can help decrease the need for morphine during the first 24 hours after surgery. Patients participating in the study will receive either the anesthesia technique or a placebo, and their morphine use will be monitored. The study will help determine if this method is effective in managing pain after cancer surgery.

Participants will be closely monitored throughout the study to ensure their safety and well-being. The trial will provide valuable information on whether this anesthesia technique can improve pain management for patients undergoing cancer surgery in the throat and neck area.

]]> Study on Reducing Post-Surgery Complications in Cancer Patients Using Ketorolac, Aspirin, and a Drug Combination https://clinicaltrials.eu/trial/study-on-reducing-post-surgery-complications-in-cancer-patients-using-ketorolac-aspirin-and-a-drug-combination/ Wed, 29 Apr 2026 15:04:12 +0000 https://clinicaltrials.eu/trial/study-on-reducing-post-surgery-complications-in-cancer-patients-using-ketorolac-aspirin-and-a-drug-combination/ This clinical trial is focused on patients undergoing major surgery for cancer treatment. The study aims to explore the effects of a specific treatment plan on reducing complications after surgery. The treatment involves a combination of medications and dietary changes. Before surgery, patients will receive an injection of ketorolac, a medication used to reduce pain and inflammation. After surgery, patients will take low-dose aspirin, which is commonly used to prevent blood clots, along with following a special diet designed to manage blood sugar levels.

The purpose of the study is to see if this combination can help reduce serious health issues that might occur within 90 days after surgery. The study will involve monitoring patients’ health and recovery over a period of time to assess the effectiveness of the treatment. Participants will be given either the treatment or a placebo to compare the outcomes. The study will also use sodium chloride solution, commonly known as saline, for infusion as part of the standard care during surgery.

By participating in this study, researchers hope to find better ways to support patients with cancer who are undergoing major surgeries, aiming to improve their recovery and reduce the risk of complications. The study will continue for several years to gather comprehensive data on the long-term benefits of the treatment plan.

]]> Study on Reducing Fluid Use During Cancer Surgery with Argipressin for Patients with Disseminated Cancer https://clinicaltrials.eu/trial/study-on-reducing-fluid-use-during-cancer-surgery-with-argipressin-for-patients-with-disseminated-cancer/ Wed, 29 Apr 2026 14:57:59 +0000 https://clinicaltrials.eu/trial/study-on-reducing-fluid-use-during-cancer-surgery-with-argipressin-for-patients-with-disseminated-cancer/ The HiPRESS study is focused on patients with disseminated cancer, which refers to cancer that has spread from its original site to other parts of the body. The study is investigating a treatment involving a medication called argipressin, also known as arginine vasopressin. This medication is being tested to see if it can reduce the amount of fluid given to patients during a specific type of surgery called cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). This surgery is used to remove as much of the cancer as possible and is followed by heated chemotherapy applied directly inside the abdomen.

The purpose of the study is to determine if using low doses of argipressin can decrease the total amount of fluid needed during the surgery compared to the standard treatment with another medication called noradrenaline. The study will involve patients who are scheduled to undergo CRS-HIPEC surgery. During the study, some patients will receive argipressin, while others will receive a placebo or the standard treatment. The effects of these treatments will be monitored to see if there is a difference in the amount of fluid required during the operation.

Participants in the study will be observed for various outcomes, including the total fluid given during surgery, fluid balance after surgery, and any signs of fluid overload. The study will also look at potential complications, such as abdominal or lung issues, and the overall recovery quality. The length of hospital stay and any serious complications up to 30 days after surgery will also be recorded. The study aims to provide valuable information on whether argipressin can improve the management of fluid levels during this complex cancer surgery.

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