Bone hypertrophy – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:37:16 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Bone hypertrophy – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study of Pamidronate for Pain Relief in Patients with Sternocostoclavicular Hyperostosis (SCCH) https://clinicaltrials.eu/trial/study-on-pamidronate-disodium-for-pain-relief-in-patients-with-sternocostoclavicular-hyperostosis/ Wed, 29 Apr 2026 15:01:08 +0000 https://clinicaltrials.eu/trial/study-on-pamidronate-disodium-for-pain-relief-in-patients-with-sternocostoclavicular-hyperostosis/ This study focuses on patients with Sternocostoclavicular hyperostosis, a rare condition that causes inflammation and abnormal bone growth in the chest wall, particularly affecting the breastbone, ribs, and collarbone area. The research evaluates the effectiveness of pamidronate, a medication given through intravenous infusion, in reducing pain associated with this condition.

The study aims to determine if pamidronate treatment given every three months can significantly decrease pain in patients compared to placebo. During the study, participants will receive either pamidronate or a sodium chloride solution (placebo) through an intravenous infusion. The maximum treatment period is 12 months.

The treatment involves receiving infusions at regular intervals, with the medication dose not exceeding 30 milligrams per day or 90 milligrams in total. Patients’ pain levels will be monitored throughout the study period using standardized pain assessment tools. The study will also track changes in movement ability, general health, and daily activities to understand how the treatment affects patients’ quality of life.

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