Blood disorder – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:34:48 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Blood disorder – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on the Role of Vitamin D (Colecalciferol) in Preventing Graft-Versus-Host Disease in Patients Undergoing Stem Cell Transplantation https://clinicaltrials.eu/trial/study-on-the-role-of-vitamin-d-colecalciferol-in-preventing-graft-versus-host-disease-in-patients-undergoing-stem-cell-transplantation/ Wed, 29 Apr 2026 14:57:37 +0000 https://clinicaltrials.eu/trial/study-on-the-role-of-vitamin-d-colecalciferol-in-preventing-graft-versus-host-disease-in-patients-undergoing-stem-cell-transplantation/ This clinical trial is focused on studying the role of Vitamin D in preventing a condition called Graft-versus-Host Disease (GVHD) in patients who are undergoing a type of treatment known as allogeneic stem cell transplantation. This treatment is often used for patients with certain blood-related diseases that require a transplant of stem cells, which are special cells that can develop into different types of blood cells. The study will use a form of Vitamin D called colecalciferol, which is administered as an oral solution known as TREDIMIN 25,000 U.I.

The purpose of the study is to evaluate how effective Vitamin D is in reducing the severity of both acute and chronic forms of GVHD. Participants in the study will receive either the Vitamin D treatment or a placebo. The study will monitor the participants over a period of time to observe any changes in the severity of GVHD and to assess the impact of Vitamin D on certain immune cells in the blood. Additionally, the study will look at how Vitamin D interacts with specific proteins on these immune cells and will collect information on any side effects that may occur from taking colecalciferol.

This study is designed to gather important information that could help improve the care of patients undergoing stem cell transplants by potentially reducing the risk or severity of GVHD. The findings from this study may contribute to better understanding and management of this condition in the future.

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