Bacterial disease carrier – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Thu, 28 May 2026 11:32:30 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Bacterial disease carrier – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A study evaluating the effectiveness of cineole compared to mupirocin in patients with chronic Staphylococcus aureus infection or carriage in the nasal cavity. https://clinicaltrials.eu/trial/a-study-to-compare-the-effectiveness-of-cineole-and-mupirocin-in-patients-with-chronic-staphylococcus-aureus-infections-in-the-nasal-cavity/ Wed, 29 Apr 2026 15:09:51 +0000 https://clinicaltrials.eu/trial/a-study-to-compare-the-effectiveness-of-cineole-and-mupirocin-in-patients-with-chronic-staphylococcus-aureus-infections-in-the-nasal-cavity/ This study focuses on individuals with chronic rhinitis, which is a long-term inflammation of the nose, specifically caused by the presence of Staphylococcus aureus in the nasal cavity. This condition involves the carrying of bacteria in the nose, including a specific type known as methicillin-resistant Staphylococcus aureus, often referred to as MRSA. This type of bacteria is resistant to many common antibiotics, making it harder to eliminate.

The purpose of the study is to evaluate the effectiveness of CINEOLE compared to mupirocin. CINEOLE is an oral treatment containing cineole, while mupirocin is a medication used through the nose. Participants in the study will undergo a course of treatment to determine how well these substances can reduce the presence of the bacteria in the nasal passages.

During the study, participants will receive one of the treatments for a period of time. Following the treatment, medical evaluations will be conducted to monitor the bacteria levels through a nasal cavity culture, which is a laboratory test used to identify and count the germs present in the nose. Follow-up checks may also be performed to see how long the effects of the treatment last.

]]> Study on the Effectiveness of Povidone-Iodine for Nasal Decolonization in Patients with MRSA https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-povidone-iodine-for-nasal-decolonization-in-patients-with-mrsa/ Wed, 29 Apr 2026 14:24:58 +0000 https://clinicaltrials.eu/trial/study-on-the-effectiveness-of-povidone-iodine-for-nasal-decolonization-in-patients-with-mrsa/ This clinical trial is focused on studying the effectiveness of a treatment for patients with (Methicillin-resistant Staphylococcus aureus), a type of bacterial infection that is resistant to many antibiotics. The treatment being tested is a nasal gel containing , a substance known for its ability to kill bacteria. The purpose of the study is to evaluate how well this nasal gel can remove MRSA from the nose of patients.

Participants in the study will use a nasal gel as part of a complete decolonization kit. The study will observe the rate at which MRSA is cleared from the nose six hours after applying the gel. The study will also assess how acceptable the treatment is to patients and healthcare workers through a questionnaire. Additionally, the study will monitor any side effects reported by patients and check the MRSA status again 24 hours after using the kit.

The trial aims to provide valuable information on the effectiveness of the nasal gel in reducing MRSA in patients. This could potentially lead to better treatment options for those affected by this resistant bacterial infection. The study will be conducted over a period, with results expected to help understand the characteristics of patients who remain MRSA positive after using the gel.

]]> Title: “Study comparing standard decolonization therapy alone versus combined with oral clindamycin for patients with MRSA throat carriage” https://clinicaltrials.eu/trial/study-on-treating-mrsa-throat-carriage-with-standard-therapy-and-oral-clindamycin-for-patients-with-mrsa-throat-carriage/ Wed, 29 Apr 2026 14:22:45 +0000 https://clinicaltrials.eu/trial/study-on-treating-mrsa-throat-carriage-with-standard-therapy-and-oral-clindamycin-for-patients-with-mrsa-throat-carriage/ This study focuses on treating people who carry Methicillin-Resistant Staphylococcus Aureus (MRSA) in their throat. MRSA is a type of bacteria that is resistant to many common antibiotics and can cause serious infections. The standard treatment includes nasal ointment containing mupirocin and body wash with chlorhexidine, which are substances used to remove bacteria from the body.

The purpose of this research is to determine if adding an oral antibiotic called clindamycin to the standard treatment works better at eliminating MRSA from the throat. During the study, some participants will receive clindamycin along with the standard treatment, while others will receive a placebo with the standard treatment.

The treatment period lasts for 10 days, during which participants take the medication by mouth. The maximum daily dose of clindamycin is 1800 mg. The effectiveness of the treatment will be checked by taking throat swabs after one month and again after six months to see if the MRSA bacteria are still present.

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