Atypical teratoid/rhabdoid tumour of CNS – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:29:01 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Atypical teratoid/rhabdoid tumour of CNS – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Atypical Teratoid/Rhabdoid Tumors in Children Using Dactinomycin, Carboplatin, and Cyclophosphamide https://clinicaltrials.eu/trial/study-on-atypical-teratoid-rhabdoid-tumors-in-children-using-dactinomycin-carboplatin-and-cyclophosphamide/ Wed, 29 Apr 2026 14:23:58 +0000 https://clinicaltrials.eu/trial/study-on-atypical-teratoid-rhabdoid-tumors-in-children-using-dactinomycin-carboplatin-and-cyclophosphamide/ This clinical trial is focused on studying a rare type of brain tumor in children known as atypical teratoid/rhabdoid tumors (ATRT). The study aims to evaluate the effectiveness of different treatment approaches for children with ATRT. The treatments being tested include high-dose chemotherapy (HDCT) and focal radiotherapy, which are used as consolidation therapies. Consolidation therapy is a treatment given after the initial therapy to strengthen its effects and help prevent the cancer from returning.

The trial involves several medications, including dactinomycin, carboplatin, cyclophosphamide, ifosfamide, etoposide, vincristine sulfate, thiotepa, doxorubicin hydrochloride, and methotrexate. These medications are administered through intravenous use, meaning they are given directly into a vein. The study is designed to compare the outcomes of children receiving these treatments to those who receive standard care, as well as to historical data from previous patients.

The purpose of the study is to determine if the new treatment approaches are as effective as, or better than, the current standard treatments. The trial will follow participants over a period of time to assess their overall survival and other health outcomes. This research is important for improving treatment options and outcomes for children diagnosed with ATRT.

]]>