Artificial insemination – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 10:30:47 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Artificial insemination – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Study on Pregnancy Rates in Women with Polycystic Ovary Syndrome Using Letrozole and Gonadotropins https://clinicaltrials.eu/trial/study-on-pregnancy-rates-in-women-with-polycystic-ovary-syndrome-using-letrozole-and-gonadotropins/ Wed, 29 Apr 2026 14:26:36 +0000 https://clinicaltrials.eu/trial/study-on-pregnancy-rates-in-women-with-polycystic-ovary-syndrome-using-letrozole-and-gonadotropins/ This clinical trial is focused on studying the effectiveness of two different treatments for women with Polycystic Ovary Syndrome (PCOS), a condition that affects the ovaries and can lead to fertility issues. The study compares the use of a medication called Letrozole with a group of medications known as gonadotropins, which include GONAL-f, Ovaleap, Puregon, and Bemfola. These treatments are used to stimulate the ovaries in preparation for artificial insemination, a procedure that helps achieve pregnancy.

The purpose of the study is to determine if Letrozole can be an effective alternative to gonadotropins in terms of pregnancy rates and live birth rates for women undergoing artificial insemination. Participants in the study will receive either Letrozole or one of the gonadotropins for a period of up to 21 days. The study will monitor the number of pregnancies achieved, as well as the number of live births resulting from the treatments. Additionally, the study will observe other factors such as the number of follicles (small sacs in the ovaries) that develop, any cancellations due to lack of response or over-response to the treatment, and any side effects like insulin resistance or gestational diabetes.

Throughout the study, participants will undergo regular check-ups, including ultrasounds to monitor the development of follicles and blood tests to assess hormone levels. The study aims to provide valuable information on the effectiveness and safety of these treatments for women with PCOS who are seeking to become pregnant through artificial insemination.

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