Adenomyosis – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Fri, 12 Jun 2026 11:24:26 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Adenomyosis – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 A study to evaluate the effect of valproic acid in women of reproductive age with adenomyosis https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effect-of-valproic-acid-in-women-of-reproductive-age-with-adenomyosis/ Wed, 29 Apr 2026 15:09:49 +0000 https://clinicaltrials.eu/trial/a-study-to-evaluate-the-effect-of-valproic-acid-in-women-of-reproductive-age-with-adenomyosis/ This study focuses on Adenomyosis, a condition where the tissue that normally lines the uterus grows into the muscular wall of the uterus. This condition can cause pelvic pain and heavy periods. The purpose of the study is to evaluate the effect of valproic acid in women with this condition.

Participants may receive valproic acid through an intralesional administration, which means the medicine is injected directly into the affected area, followed by taking valproic acid as an oral medication. Other participants might receive sodium chloride through an injection into the affected area, followed by a placebo taken orally. Some individuals may also use ibuprofen as a rescue medication to help manage pain during the study period.

]]> Study on the Effect of Triptorelin Before Frozen Embryo Transfer in Patients with Endometriosis or Adenomyosis https://clinicaltrials.eu/trial/study-on-the-effect-of-triptorelin-before-frozen-embryo-transfer-in-patients-with-endometriosis-or-adenomyosis/ Wed, 29 Apr 2026 14:57:44 +0000 https://clinicaltrials.eu/trial/study-on-the-effect-of-triptorelin-before-frozen-embryo-transfer-in-patients-with-endometriosis-or-adenomyosis/ This clinical trial is focused on studying the effects of a treatment for women with endometriosis and/or adenomyosis. These are conditions where tissue similar to the lining inside the uterus grows outside of it, causing pain and other symptoms. The treatment being tested is a medication called triptorelin, which is a type of drug known as a GnRH agonist. This medication is given as a prolonged-release injection, meaning it is designed to release slowly over time to provide long-lasting effects.

The purpose of the study is to see if using triptorelin before a procedure called frozen embryo transfer (FET) can improve pregnancy rates in women undergoing assisted reproductive technology (ART). In this study, some participants will receive the triptorelin treatment, while others will receive a placebo. The study will monitor the clinical pregnancy rates, which means checking for a fetal heartbeat during an ultrasound at the final visit.

Participants will be followed throughout the study to observe the number of successful embryo implantations, any miscarriages, and any side effects related to low estrogen levels, such as hot flashes or mood swings. The study aims to provide valuable information on whether this treatment can help improve outcomes for women with endometriosis and/or adenomyosis who are trying to conceive through ART.

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