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	<title>Abortion threatened &#8211; European Clinical Trials Information Network</title>
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	<title>Abortion threatened &#8211; European Clinical Trials Information Network</title>
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		<title>Comparison of ceftriaxone and azithromycin versus amoxicillin and azithromycin for pregnant women with preterm premature rupture of membranes between 22 and 33 weeks.</title>
		<link>https://clinicaltrials.eu/trial/comparison-of-ceftriaxone-and-azithromycin-versus-amoxicillin-and-azithromycin-for-pregnant-women-with-preterm-premature-rupture-of-membranes-between-22-and-33-weeks/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Thu, 30 Apr 2026 13:08:56 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/comparison-of-ceftriaxone-and-azithromycin-versus-amoxicillin-and-azithromycin-for-pregnant-women-with-preterm-premature-rupture-of-membranes-between-22-and-33-weeks/</guid>

					<description><![CDATA[This study focuses on women experiencing Preterm Premature Rupture of Membranes, a condition where the protective sac around a developing baby breaks too early in pregnancy. The purpose of the study is to compare different antibiotic treatments to see which is more effective at preventing health problems for the baby and the mother. The medications [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This study focuses on women experiencing <b>Preterm Premature Rupture of Membranes</b>, a condition where the protective sac around a developing baby breaks too early in pregnancy. The purpose of the study is to compare different antibiotic treatments to see which is more effective at preventing health problems for the baby and the mother. The medications being studied include <b>ceftriaxone</b> and <b>azithromycin</b>, which will be compared against a combination of <b>amoxicillin</b> and <b>azithromycin</b>.</p>
<p>Participants in the study will receive one of the two antibiotic regimens. One group will receive <b>ceftriaxone</b> through an <b>intravenous</b>, <b>subcutaneous</b>, or <b>intramuscular</b> method, which means the medicine is delivered via an injection into a vein, under the skin, or into a muscle. The other group will receive <b>amoxicillin</b> or <b>azithromycin</b> through <b>oral use</b>, meaning the medicine is taken by mouth. The study follows these patients to monitor the health of the baby and the mother during and after the pregnancy.</p>
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		<title>Study on Antibiotic Combination of Ceftriaxone, Clarithromycin, and Metronidazole for Pregnant Women with Threatened Miscarriage and Intact Membranes</title>
		<link>https://clinicaltrials.eu/trial/study-on-antibiotic-combination-of-ceftriaxone-clarithromycin-and-metronidazole-for-pregnant-women-with-threatened-miscarriage-and-intact-membranes/</link>
		
		<dc:creator><![CDATA[]]></dc:creator>
		<pubDate>Wed, 29 Apr 2026 14:59:16 +0000</pubDate>
				<guid isPermaLink="false">https://clinicaltrials.eu/trial/study-on-antibiotic-combination-of-ceftriaxone-clarithromycin-and-metronidazole-for-pregnant-women-with-threatened-miscarriage-and-intact-membranes/</guid>

					<description><![CDATA[This clinical trial is focused on improving outcomes for pregnancies that are at risk of a late miscarriage, which is when a pregnancy ends unexpectedly between 18 and 24 weeks. The study involves pregnant women who are experiencing signs of a possible miscarriage but still have intact membranes, meaning the protective sac around the baby [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>This clinical trial is focused on improving outcomes for pregnancies that are at risk of a late miscarriage, which is when a pregnancy ends unexpectedly between 18 and 24 weeks. The study involves pregnant women who are experiencing signs of a possible miscarriage but still have intact membranes, meaning the protective sac around the baby has not broken. The goal is to reduce the risk of losing the baby and to improve the health of newborns by extending the pregnancy as long as possible.</p>
<p>The trial will test a combination of antibiotics to see if they can help achieve this goal. The medications being studied include <em>CEFTRIAXONE</em>, which is given as an injection, <em>CLARITHROMYCIN</em>, and <em>METRONIDAZOLE</em>, both of which are taken as tablets. These antibiotics are commonly used to treat infections and may help in preventing complications that could lead to a miscarriage or affect the baby&#8217;s health.</p>
<p>Participants in the study will be randomly assigned to receive either the combination of antibiotics or a placebo. The study will monitor the health of the mother and baby throughout the pregnancy and after birth to assess the effectiveness of the treatment. The trial aims to provide valuable information that could lead to better care for pregnancies at risk of late miscarriage.</p>
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