Abortion spontaneous – European Clinical Trials Information Network https://clinicaltrials.eu Bridging Patients with Clinical Trials Wed, 27 May 2026 13:12:11 +0000 en-US hourly 1 https://wordpress.org/?v=7.0 https://clinicaltrials.eu/wp-content/uploads/2024/12/cropped-EU_icon-32x32.png Abortion spontaneous – European Clinical Trials Information Network https://clinicaltrials.eu 32 32 Comparing hysteroscopic surgery to mifepristone and misoprostol treatment for early pregnancy loss in women under 10 weeks of pregnancy https://clinicaltrials.eu/trial/comparing-hysteroscopic-surgery-to-mifepristone-and-misoprostol-treatment-for-early-pregnancy-loss-in-women-under-10-weeks-of-pregnancy/ Wed, 29 Apr 2026 15:07:53 +0000 https://clinicaltrials.eu/trial/comparing-hysteroscopic-surgery-to-mifepristone-and-misoprostol-treatment-for-early-pregnancy-loss-in-women-under-10-weeks-of-pregnancy/ This study involves women who have experienced an early pregnancy loss, which means a miscarriage that happens before 10 weeks of pregnancy. When a pregnancy loss occurs, the tissue from the pregnancy needs to be removed from the womb. There are different ways to do this, and this study compares two of these methods. The first method is called hysteroscopic resection, which is a procedure where a thin tube with a camera is inserted through the vagina into the womb to remove the pregnancy tissue. The second method is medical management, which uses medications to help the body expel the pregnancy tissue naturally. The medications used in this study are mifepristone, which is taken by mouth, and misoprostol, which is placed in the vagina.

The purpose of this study is to compare these two treatment methods to see which one works better at completely removing the pregnancy tissue, and to look at any problems that might happen either soon after treatment or later on. The study will also look at whether women are able to get pregnant again after treatment and how satisfied they feel with their care. Women who take part will be randomly assigned to receive either the surgical procedure or the medication treatment. After the treatment, they will have follow-up visits that include an ultrasound scan, which uses sound waves to create pictures of the inside of the womb, and a diagnostic hysteroscopy, which is an examination of the womb using a thin camera.

During the follow-up period, which happens about one to two months after treatment, doctors will check whether all the pregnancy tissue has been removed or if any tissue remains in the womb. They will also look for any scarring inside the womb that might have formed after treatment. Women in the study will be asked to complete questionnaires about how they are feeling and their quality of life at different times after their treatment. The study will also collect information about any complications that occur within 30 days of treatment and will track whether women become pregnant again in the year following their participation in the study.

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