Clinical trials located in

Terrassa

Terrassa city is located in Spain. Currently, 11 clinical trials are being conducted in this city.

Terrassa, nestled in the eastern Vallès Occidental region of Spain, boasts a rich tapestry of history and culture. Known for its remarkable architectural heritage, the city is home to the Terrassa Cathedral and the striking ensemble of the Churches of Sant Pere, showcasing Romanesque artistry. Its industrial past is evident in its modernist buildings and the Vapor Aymerich, Amat i Jover, now the Science and Technology Museum of Catalonia. Terrassa also prides itself on its vibrant arts scene, with numerous festivals and a thriving music culture, reflecting its dynamic spirit.

  • CT-EU-00034263

    Treatment of lung cancer before and after surgery using various drug combinations

    The NeoCOAST-2 trial is a phase II study evaluating various combinations of anticancer therapies in patients with resectable early-stage non-small cell lung cancer. This study is divided into two stages. The first stage occurs before surgery (neoadjuvant treatment), the next stage after surgery (adjuvant treatment). Researchers will use a drug called Durvalumab, which will be combined with various drugs. The goal is to determine the safety and effectiveness of these regimens for treating early-stage lung cancer, potentially improving treatment outcomes.

    The first group of patients will receive Oleclumab, Durvalumab and a strong drug – Carboplatin/Paclitaxel Pemetrexed/Cisplatin Pemetrexed/Carboplatin. After surgery, they will be given Oleclumab and Durvalumab.

    Patients in the second group will receive Monalizumab, Durvalumab and drugs combined with platinum before surgery. After surgery, they will be given Monalizumab and Durvalumab.

    In the third group, MEDI5752 and drugs combined with platinum are administered before surgery. After surgery, patients will only receive MEDI5752.

    People from group four receive Dato-DXd, Durvalumab, Carboplatin or Cisplatin before surgery. After surgery, they will be given Durvalumab.

    Participants in the fifth group will receive AZD0171, Durvalumab and platinum doublet chemotherapy before surgery. After surgery, patients will receive AZD0171 and Durvalumab.

    BelgiumFranceHungaryItalyPortugalSpain
  • Testing new medicine for resistant high blood pressure

    In this 20-week trial, the effectiveness, safety, and optimal dosage of a medication known as XXB750 are being evaluated in individuals with resistant high blood pressure (resistant hypertension). This condition persists despite the use of three different blood pressure medications. XXB750 will be administered through subcutaneous injections, and its efficacy will be compared to a placebo. A 2-week preparation period precedes the trial, during which participants receive three doses of the actual trial medicine and one dose as part of the preparation. Following the trial, participants will be monitored for an additional 8 weeks without receiving any trial medicine during this period. The primary focus is on assessing whether XXB750 can effectively reduce blood pressure when measured over a 24-hour period.

    AustriaBulgariaCzechiaFranceGermanyItalyNetherlandsPolandSlovakiaSpainUnited Kingdom
  • Evaluating epilepsy treatment with brivaracetam

    This study aims to see how effective and safe a drug called Brivaracetam is for children and young adults aged between 2 and 25 who have a type of epilepsy known as Absence Epilepsy. Brain activity will be recorded for 24 hours using a device on day 14. If the patient has not had an episode of epilepsy in the 4 days before the recording or during it, they are considered ‘free’ of seizures. If the patients experience a seizure, it will be recorded on the machine and these patients have to leave the study. These patients also should not be taking a type of drug known as benzodiazepine during the study. All people taking part will have to keep a diary of their seizures from the start of the study until the end.

    BelgiumItalyRomaniaSlovakiaSpain
  • Evaluating different drugs for advanced multiple myeloma

    This study is conducted to see how good a medication called Elranatamab is for individuals having multiple myeloma, a blood cancer that affects the marrow inside your bones. This study will use Elranatamab alone, or pair it with another medication called Daratumumab. The aim is to see if Elranatamab alone or mixed with Daratumumab is better than the current treatment of Daratumumab mixed with two other medications named Pomalidomide and Dexamethasone. This research is primarily for individuals who have undergone previous treatments with medications, Lenalidomide and a proteasome inhibitor. The study has two parts. The aim of the first part is the safety test and effects of Elranatamab mixed with Daratumumab at various doses. The second part will divide participants into three groups: Elranatamab alone, Elranatamab with Daratumumab, or the current treatment. The goal is to observe which treatment is safer and works better.

    AustriaCzechiaFranceGermanyGreeceItalyPolandSpainSwedenUnited Kingdom
  • Testing Milvexian’s effectiveness in preventing repeat strokes

    This research trial, called LIBREXIA-STROKE, will test a medication called Milvexian on those who have recently had a stroke or a high-risk ‘mini-stroke’. In its 3rd testing phase, the study will involve a system where the patients won’t know whether they are receiving the actual drug or a substitute with no effect, referred to as a ‘placebo’, to maintain fairness. Milvexian is a medication that can potentially reduce the risk of having another stroke, and this trial aims to observe how effective it is in doing so. The trial will look at when the first stroke happens after starting the trial, if other major heart or limb diseases occur, or if strokes occur in the first 90 days.

    AustriaBelgiumBulgariaCzechiaDenmarkFinlandFranceGermanyHungaryItalyNetherlandsPolandPortugalRomaniaSlovakiaSpainSwedenUnited Kingdom
  • Comparison of different treatments for follicular lymphoma

    This study involves comparing two treatments for a condition known as follicular or marginal zone lymphoma, both of which are types of cancer affecting lymph cells. The first treatment combines zanubrutinib with an antibody called Anti-CD20, while the second treatment involves lenalidomide and rituximab. These treatments are intended for patients who have not responded or have stopped responding to conventional treatment. One of the primary objectives of the study is to determine which treatment is more effective in preventing the cancer from progressing, referred to as progression-free survival. Additionally, the study aims to assess the impact of these treatments on the patients’ quality of life, evaluating various aspects through questionnaires related to physical and emotional well-being, symptoms, and the ability to perform normal activities.

    AustriaCzechiaFranceItalyRomaniaSpainUnited Kingdom
  • Study on dazostinag & pembrolizumab for advanced solid tumors

    The purpose of this study is to test a new drug called dazostinag. A study is being conducted to see whether this drug is helpful in adults with advanced forms of solid cancer. Some people are given dazostinag alone, while others are given it with another medicine called pembrolizumab. Scientists’ focus here is on finding out whether these drugs cause any side effects, and finding out what the maximum dose is that people can take without serious side effects. The study consists of two parts, including a dose escalation phase and a dose escalation phase. In the first part, the dose of dazostinag will be gradually increased, given alone or in combination with pembrolizumab. In the second part, Dazostinag will be tested with pembrolizumab and other anticancer drugs. This section will focus on patients with specific cancers that are difficult to remove or have spread to other parts of the body.

    AustriaBelgiumFrancePolandUnited Kingdom
  • Baxdrostat in resistant hypertension: safety and efficacy study

    This study is testing a medication named baxdrostat in people who have high blood pressure that can’t be controlled with their current medication. The study will compare people who are given baxdrostat daily with people who are given a placebo. The goal of the study is to find out if baxdrostat is safe to take and if it helps lower blood pressure. The study will look at the effects of 1 mg and 2 mg doses of baxdrostat on blood pressure. The study will also look at whether Baxdrostat helps reach a blood pressure reading below 130 mmHg.

    AustriaBelgiumBulgariaCzechiaDenmarkFranceGermanyHungaryItalyNetherlandsPolandSlovakiaSpainSwedenUnited Kingdom
  • A study on the treatment of multiple myeloma using a combination of innovative and standard drugs

    This clinical trial is dedicated to evaluating the long-term effectiveness and safety of two novel drug combinations, Teclistamab with Daratumumab and Lenalidomide (Tec-DR) and Talquetamab with Daratumumab and Lenalidomide (Tal-DR), for patients newly diagnosed with multiple myeloma. The study is designed as a randomized, parallel assignment trial, involving about 1590 participants. By comparing these new treatments against the standard combination of Daratumumab, Lenalidomide, and Dexamethasone (DRd), the research aims to identify the most effective treatment protocol for managing this type of cancer, potentially leading to new standard care practices for multiple myeloma.

    BelgiumCzechiaFranceGermanyItalyNetherlandsPolandSpainSwedenUnited Kingdom
  • Study of new drugs in acute lymphoblastic leukemia

    This clinical trial focuses on improving treatment strategies for acute lymphoblastic leukemia (ALL) in a diverse age group, from infants to young adults up to 45 years old. The study combines standard treatments with new drugs, for example, Inotuzumab Ozogamicin and Blinatumomab. The trial aims to tailor treatment to individual patient needs and reduce toxicity while maintaining treatment quality. By carefully monitoring event- and disease-free survival rates, as well as minimal residual disease responses, the trial aims to improve the standard of care for ALL and improve both survival outcomes and patient quality of life.

    BelgiumDenmarkFinlandFranceGermanyNetherlandsNorwayPortugalSwedenUnited Kingdom
  • Exploring sacituzumab govitecan for HER2-negative breast cancer care

    This study is evaluating a new treatment for patients with a certain type of breast cancer (HER2-negative) who have not had a complete response to initial chemotherapy. Participants are randomly assigned to receive the investigational drug sacituzumab govitecan or a treatment of their physician’s choice, which may be another type of chemotherapy with capecitabinalub, carboplatin or cisplatin. The study is designed to compare the effectiveness of these approaches in preventing cancer recurrence. Patients may also receive hormone therapy if needed. Patients’ safety and response to treatment are being closely monitored throughout the study.

    AustriaBelgiumFranceGermanyItalySpain

See more clinical trials in other cities in Spain:

.