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Uncategorized

  • First‑line Study of RMC‑9805 with Investigator’s Choice Chemotherapy Drug Combination vs Chemotherapy Alone in Patients with Metastatic KRAS G12D‑Mutated Pancreatic Adenocarcinoma

    Not yet recruiting

    3 1
    Investigated Drugs:
    • (2S)-2-CYCLOPENTYL-2-[(5S)-2-[(2R,3R)-3-CYCLOPROPYL-1-METHYLAZIRIDINE-2-CARBONYL]-2,7-DIAZASPIRO[4.4]NONAN-7-YL]-N-[(6S,8S,14S)-21-[5-(4-CYCLOPROPYLPIPERAZIN-1-YL)-2-[(1S)-1-METHOXYETHYL]PYRIDIN-3-YL]-18,18-DIMETHYL-9,15-DIOXO-22-(2,2,2-TRIFLUOROETHYL)-5,16-DIOXA-2,10,22,28-TETRAZAPENTACYCLO[18.5.2.12,6.110,14.023,27]NONACOSA-1(26),20,23(27),24-TETRAEN-8-YL]ACETAMIDE
    Belgium Czechia Denmark France Germany Italy +2

  • Safety and Pharmacokinetics of MIB2 (StaphAcute) in Healthy Volunteers and Patients with Staphylococcus aureus Bacteremia

    Not yet recruiting

    2 1 1
    Investigated Diseases:
    • Staphylococcal bacteraemia
    Investigated Drugs:
    • Sodium Chloride
    Germany

  • Adalimumab, Doxycycline, and Resorcinol for Adults with Early Hidradenitis Suppurativa at High Risk of Progression to Severe Disease

    Not yet recruiting

    3 1 1 1
    Investigated Diseases:
    • Hidradenitis
    Investigated Drugs:
    • Doxycycline
    • Adalimumab
    Denmark

  • Phase 3 study of mitapivat for effectiveness and safety in children with non‑transfusion‑dependent alpha or beta thalassemia

    Not yet recruiting

    3 1
    Investigated Drugs:
    • Mitapivat
    Greece Italy

  • Privosegtor Added to Standard IV Methylprednisolone in Patients with Optic Neuritis: Randomized Placebo‑Controlled Trial

    Not yet recruiting

    3 1
    France Germany Italy Spain

  • A Randomized Double‑Blind Study of Pharmacokinetic Similarity of AVT32‑DRL_PB and Pembrolizumab in Patients with Resected Stage IIB‑C‑III Melanoma

    Not yet recruiting

    3 1 1 1
    Investigated Drugs:
    • Pembrolizumab
    Romania Spain
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