Mometasone nasal spray is a steroid spray used in the nose to reduce inflammation and relieve symptoms of allergic rhinitis such as sneezing, runny nose, and congestion. In the trial it was allowed as a background medication for participants who needed ongoing nasal steroid therapy.
Budesonide nasal spray is another nasal steroid that helps calm inflamed nasal passages and eases allergy symptoms. Participants could continue using it during the study if it was part of their regular treatment.
Bilastine tablets are oral antihistamine pills that block the action of histamine, a chemical that causes itching, sneezing, and watery eyes in allergies. They were permitted as a background medication for people who required daily allergy relief.
Triamcinolone acetonide nasal spray is a steroid spray that reduces swelling in the nasal lining, helping to control nasal allergy symptoms. It could be used by participants as part of their usual care.
Grass pollen skin‑prick test solution (Phleum pratense) is a small amount of grass pollen extract applied to the skin to check if a person is allergic to grass pollen. It was used in the study to confirm participants’ allergy status.
Emedastine eye drops are eye‑drop medication that relieves itchy, red, and watery eyes caused by allergic reactions. Participants could continue using them if they already needed eye‑drop treatment.
Ebastine tablets are oral antihistamine pills that help control sneezing, itching, and runny nose by blocking histamine. They were allowed as background therapy for allergic symptoms.
Cetirizine tablets are commonly used oral antihistamines that reduce allergy signs such as sneezing and itching. They could be taken by participants during the trial.
Desloratadine tablets are non‑sedating antihistamine pills that help relieve nasal and eye allergy symptoms. Participants were permitted to use them as part of their regular allergy regimen.
Fexofenadine tablets are oral antihistamines that relieve allergy symptoms without causing drowsiness. They were allowed as background medication.
Fluticasone furoate nasal spray is a steroid spray that reduces nasal inflammation and congestion associated with allergies. Participants could keep using it if it was part of their normal treatment.
Bilastine eye drops are eye‑drop antihistamines that help relieve itchy and watery eyes caused by allergies. They could be used by participants who needed eye‑drop therapy.
Cat epithelia skin‑prick test solution contains proteins from cat skin and is used to test for cat allergy by a small skin prick. It helped confirm participants’ sensitivity to cat allergens.
Olopatadine eye drops are antihistamine eye drops that reduce itching, redness, and tearing caused by allergic eye reactions. Participants could continue using them if prescribed.
Mannan‑conjugated allergoid vaccine (grass pollen) is the investigational product being tested. It is a specially processed mixture of grass pollen proteins (from Phleum pratense and Dactylis glomerata) linked to a harmless sugar molecule (mannan) to reduce allergic reactions while stimulating the immune system. It was given by subcutaneous injection at two different concentrations to see which works best for treating grass‑pollen allergic rhinitis.
Histamine dihydrochloride positive control solution is a tiny amount of histamine used during skin‑prick testing to show that the skin reacts normally. It served as a reference point for the allergy skin tests in the study.
Rupatadine tablets are oral antihistamines that also have anti‑inflammatory effects, helping to control nasal and eye allergy symptoms. They could be used by participants as part of their usual care.
Dog epithelia skin‑prick test solution contains proteins from dog skin and is used to test for dog allergy through a small skin prick. It helped identify participants with dog‑related allergic sensitivity.
Histamine dihydrochloride positive control (alternative preparation) is another form of the histamine reference solution used during skin‑prick testing to confirm proper skin reactivity.
Alternaria alternata skin‑prick test solution contains mold spores from the fungus Alternaria and is used to test for mold allergy. It was part of the allergy testing panel.
Azelastine eye drops are antihistamine eye drops that quickly relieve itchy, red, and watery eyes caused by allergies. Participants could keep using them if needed.
Grass pollen mixture skin‑prick test solution combines extracts from many common grass species to test for broad grass‑pollen allergy. It helped verify participants’ sensitivity to a range of grass pollens.
Levocetirizine tablets are a newer, non‑sedating antihistamine that reduces sneezing, itching, and runny nose. They were allowed as background therapy.
Dermatophagoides pteronyssinus skin‑prick test solution contains dust‑mite allergen and is used to test for house‑dust‑mite allergy by a small skin prick. It helped confirm participants’ allergic status.
Levocabastine eye drops are antihistamine eye drops that relieve allergic eye symptoms such as itching and tearing. They could be used by participants during the trial.
Loratadine tablets are oral antihistamines that help control nasal and eye allergy symptoms without causing strong drowsiness. They were permitted as background medication.
Negative control solution (water for injection) is a harmless saline solution used in skin‑prick testing to show what a non‑reactive result looks like. It served as a baseline for the allergy tests.
Negative control solution (phenol) is another non‑reactive solution used in skin‑prick testing to ensure the skin’s response is specific to allergens. It acted as a negative control.
Ciclesonide inhalation solution is an inhaled steroid used for asthma and can also reduce airway inflammation. Participants with asthma could continue using it as part of their regular treatment.
Fluticasone propionate nasal spray is a steroid nasal spray that decreases swelling in the nose to improve breathing and reduce allergy symptoms. It was allowed as a background medication.
Germany 
