Ibuzatrelvir is an antiviral medication being studied for treating COVID-19 in people with weakened immune systems. It works by blocking a protein that the virus needs to multiply in the body. This medication is taken orally to help fight the coronavirus infection.

Remdesivir is an established antiviral medication that is already approved for treating COVID-19. It works by interfering with the virus’s ability to copy itself. This medication is given through an intravenous (IV) line directly into the bloodstream.

The study also includes a combination therapy of ibuzatrelvir and remdesivir together, to see if using both medications provides better results than using either medication alone in people with severely compromised immune systems who have COVID-19.

COVID-19 – A respiratory disease caused by the SARS-CoV-2 virus that primarily affects the lungs and respiratory system. The infection typically begins with symptoms such as fever, cough, fatigue, and loss of taste or smell. The virus spreads mainly through respiratory droplets when infected people breathe, talk, cough, or sneeze. The disease can range from mild to severe, with some people experiencing difficulty breathing and decreased oxygen levels. In immunocompromised individuals, the infection may last longer and symptoms can be more persistent.