YOHIMBINE HYDROCHLORIDE

Clinical trials investigating YOHIMBINE HYDROCHLORIDE are looking at how it may affect stress-related behavior and decision-making. The available study involved military personnel and tested whether it changes moral judgment during an acute stress response. The trial focused on study outcomes such as choice patterns and decision-making errors.

Table of Contents

Trial overview

The clinical trial with YOHIMBINE HYDROCHLORIDE was titled “Understanding the Neurobiology of Pharmacologically-induced Acute Stress on Ethical Decisions” and was listed as completed.[1] It was an interventional study, which means researchers gave study treatments and then measured the effects.[1]

Who participated

The trial was designed to study the effects of yohimbine and/or hydrocortisone on moral judgment in military personnel.[1] The study enrolled 100 people.[1]

What was studied

The study aimed to observe how YOHIMBINE HYDROCHLORIDE and related study treatments affected moral judgment during a situation meant to mimic an acute stress response in humans.[1] In simple terms, the researchers wanted to see whether stress-related treatment changed how people made ethical choices.[1]

The listed interventions were cellulose microcrystalline, YOCORAL 5 mg tabletten, and Hydrocortison Teva 10 mg, all given orally in the trial record.[1] The source data does not provide more detail about how these were compared beyond their listing in the study.[1]

Main outcomes

The primary outcomes focused on the number of utilitarian, deontological, and compromise choices in a behavioral task measuring moral judgment.[1] These are different ways people may decide what to do in a difficult ethical situation.[1]

The trial also measured the number of violations in rationality when making moral decisions.[1] This means the researchers looked for choices that did not follow expected logical patterns in the task.[1]

Study design and phase

This was a Phase 3 trial.[1] Phase 3 studies are later-stage trials that usually test how well an intervention works in a larger group of people.[1]

The study was completed, so the planned research activities were finished.[1] The available data does not include results, so this article focuses on what the trial planned to measure rather than on final findings.[1]

What the study tracked

The trial tracked how people responded in a moral decision task under a stress-like condition.[1] The key idea was to see whether study treatment changed the balance between rule-based decisions, outcome-based decisions, and middle-ground choices.[1]

Because the source data is limited to one study, the clinical trial picture for YOHIMBINE HYDROCHLORIDE is narrow and specific.[1] It centers on stress, ethics, and decision-making in military personnel rather than on a broad range of diseases.[1]

Trial ID Phase Condition Studied Status Enrollment
2023-508731-31-01 Phase 3 Mimic an acute stress response in humans Completed 100

Ongoing Clinical Trials on YOHIMBINE HYDROCHLORIDE

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Glossary

  • Acute stress response: A short-term body and brain reaction to stress. In this study, the trial tried to mimic that response in humans.
  • Behavioral task: A structured activity used in research to observe how people think, choose, or act.
  • Moral judgment: The process of deciding what is right or wrong in a situation.
  • Utilitarian choice: A decision that aims to create the greatest overall benefit or least harm.
  • Deontological choice: A decision based on rules or duties, even if the outcome is less helpful overall.
  • Compromise choice: A middle-ground decision that is not fully rule-based or fully outcome-based.
  • Rationality violations: Choices that do not follow expected logical patterns in the study task.
  • Interventional study: A study where researchers give a treatment or intervention and then measure the effects.
  • Phase 3: A later-stage clinical trial that usually tests how well a treatment works in a larger group.
  • Enrollment: The number of people who joined the study.

References