HIV and Antiretroviral Therapy Research

At Azienda Sanitaria Locale Citta Di Torino, a major focus is HIV care and treatment optimization, with studies in Virus Diseases and Immune System Diseases aimed at improving long-term control of infection and simplifying therapy for people living with HIV-1.

  • Switching stable patients to newer antiretroviral combinations to maintain viral suppression
  • Testing novel oral regimens for treatment-naïve and treatment-experienced people with HIV-1
  • Evaluating safer, more convenient treatment strategies for chronic HIV management

These trials are designed to assess treatment effectiveness, support durable viral control, and expand options for patients with limited or complex prior therapy.

Kidney Disease and Nephrology Studies

The site’s SCDU Nefrologia e Dialisi – CMID department is also active in Reproductive and Urinary Physiological Phenomena research, with studies centered on chronic kidney disease, Immunoglobulin A Nephropathy (IgAN), and rapidly progressive glomerulonephritis.

  • Assessing therapies that may preserve kidney function and reduce protein loss in IgAN
  • Studying rescue approaches for severe inflammatory kidney disease
  • Exploring treatments that may slow worsening kidney disease and related complications

Overall, the research aims to improve kidney protection, evaluate safety, and identify better options for patients with progressive renal disorders.

Cardiovascular and Stroke Prevention Research

Clinical trials in Cardiovascular Diseases at this Turin site include work on preventing ischemic stroke and reducing heart-related events in people with type 2 diabetes and other high-risk conditions.

  • Testing new approaches to lower the risk of stroke after a recent cerebrovascular event
  • Evaluating therapies that may reduce major cardiovascular complications in high-risk diabetes
  • Studying strategies to improve protection against clot-related vascular events

These studies focus on prevention and cardiovascular risk reduction, with the goal of improving outcomes in patients vulnerable to serious vascular disease.

Infectious Disease and Respiratory Infection Trials

Research in Bacterial Infections and Mycoses and Respiratory Tract Diseases includes studies on tuberculosis and severe viral lung infections, reflecting a strong interest in difficult-to-treat infections.

  • Examining safer and more effective treatment approaches for tuberculosis
  • Testing therapies for hospitalized patients with serious viral lung disease
  • Looking at ways to improve infection control and clinical outcomes in severe respiratory illness

These trials are intended to support better infection treatment, improve tolerability, and address high-risk respiratory conditions.

Autoimmune, Viral Hepatitis, and Cancer Research

The site also contributes to broader Immune System Diseases, Virus Diseases, and Neoplasms research, including studies in Systemic Lupus Erythematosus, Chronic Hepatitis D Virus (HDV) Infection, and colorectal cancer.

  • Evaluating new options to reduce autoimmune disease activity in lupus
  • Studying antiviral approaches for chronic hepatitis D infection
  • Comparing treatment strategies for advanced colorectal cancer after prior therapy

Across these areas, the trials aim to improve disease control, test new therapeutic options, and refine care for patients with complex chronic illnesses.