Immunology and Inflammatory Diseases

The clinical research at Centre Hospitalier Universitaire De Nice includes a strong focus on immune system diseases and chronic inflammatory conditions. Studies are exploring better ways to manage alopecia areata, giant cell arteritis, psoriasis, vitiligo, and hidradenitis suppurativa, with the goal of improving symptom control and long-term disease management.

  • Testing new therapies for autoimmune and skin-related inflammatory disorders
  • Evaluating treatment effectiveness in chronic immune-mediated diseases
  • Improving options for patients with difficult-to-control inflammatory conditions

These trials reflect active work in both dermatology and rheumatology, with an emphasis on finding more effective and better-tolerated treatments.

Gastroenterology and Liver Disease

Research in digestive system diseases is well represented, especially for Crohn’s disease, ulcerative colitis, primary biliary cholangitis, hepatic encephalopathy, and NASH/MASH. The studies are designed to assess new treatments that may reduce inflammation, ease symptoms, and slow progression of liver and intestinal disease.

  • Evaluating therapies for inflammatory bowel disease
  • Testing treatments for liver-related complications and chronic liver inflammation
  • Improving disease control and quality of life in long-term gastrointestinal illness

This area highlights an important mix of gastroenterology and hepatology research at the site.

Hematology and Blood Cancers

The site is actively involved in hemic and lymphatic diseases, with trials in acute myeloid leukemia, myelodysplastic syndromes, myelofibrosis, lymphoma, and paroxysmal nocturnal hemoglobinuria. Research here is focused on better treatment strategies for blood cancers and related disorders that affect blood production and immune function.

  • Testing new approaches for leukemia and other hematologic malignancies
  • Assessing treatments that may reduce transfusion needs and improve blood counts
  • Studying therapies for relapsed or hard-to-treat lymphoma

These studies support ongoing advances in hematology and cancer care at Centre Hospitalier Universitaire De Nice.

Oncology and Cancer Immunotherapy

Clinical trials in neoplasms cover a broad range of cancers, including melanoma, biliary tract carcinoma, hepatocellular carcinoma, cutaneous squamous cell carcinoma, basal cell carcinoma, and Wilms tumor. The main aim is to evaluate whether new or combined cancer treatments can improve survival, prevent recurrence, or strengthen disease control after surgery or prior therapy.

  • Testing immunotherapy and targeted treatment strategies in solid tumors
  • Studying adjuvant approaches to reduce cancer recurrence
  • Evaluating options for advanced or difficult-to-treat cancers

This portfolio shows a strong commitment to oncology research, especially in cancer immunotherapy and treatment optimization.

Infectious Diseases and Respiratory Care

Research in bacterial infections, virus diseases, and respiratory tract diseases includes studies in HIV-1 infection, COVID-19, community-acquired pneumonia, and severe pneumonia. These trials aim to improve infection control, refine treatment choices, and support recovery in hospitalized patients.

  • Evaluating antiviral strategies for people living with HIV
  • Testing treatments for COVID-19 and serious respiratory infections
  • Improving antibiotic use and care in pneumonia

The work combines infectious disease and pulmonary medicine research with a practical focus on patient outcomes.

Cardiometabolic and Neurologic Research

Trials in cardiovascular diseases, nutritional and metabolic diseases, and nervous system diseases address conditions such as atherosclerotic cardiovascular disease, obesity, overweight, and migraine. The research is centered on prevention, symptom relief, and better long-term management of common chronic conditions.

  • Studying prevention strategies for cardiovascular risk
  • Testing therapies for obesity-related metabolic disease
  • Exploring improved care for migraine attacks in emergency settings

These studies broaden the site’s work across cardiology, metabolism, and neurology.

Rare and Pediatric Disorders

Some trials focus on congenital, hereditary, and neonatal diseases, including rare conditions such as recessive dystrophic epidermolysis bullosa, junctional epidermolysis bullosa, and genodermatoses. Research also includes pediatric studies in alopecia areata and psoriasis, reflecting an interest in conditions that affect children and families.

  • Testing new treatment options for rare inherited skin disorders
  • Evaluating therapies for pediatric immune-mediated diseases
  • Supporting better care for uncommon and severe lifelong conditions

This area highlights the site’s contribution to rare disease and pediatric research in France.