The study focuses on understanding how different temperatures of a fluid called Ringer’s lactate affect the body. Ringer’s lactate is a solution used in medical settings to provide essential minerals and fluids to the body. It contains substances like potassium chloride, sodium chloride, calcium chloride dihydrate, and sodium lactate. The study will compare the effects of this solution when it is cooled to 10 degrees Celsius versus when it is at room temperature, which is 22 degrees Celsius.
The purpose of the study is to see how these different temperatures of Ringer’s lactate affect healthy adults, particularly looking at how it influences blood circulation and the body’s ability to stop bleeding, known as hemostasis. Participants will receive the solution through an intravenous infusion, which means it will be delivered directly into the bloodstream through a vein. The study will observe changes in blood pressure, heart rate, and other related factors to understand the body’s response to the fluid at different temperatures.
This research is designed as a randomized crossover trial, meaning participants will receive both temperature variations of the solution at different times. The main focus is to measure changes in mean arterial pressure, which is a type of blood pressure, 30 minutes after the infusion starts. Other observations will include how long it takes for blood pressure to return to normal, changes in body temperature, and other physiological responses. The study aims to provide insights into how temperature variations in medical fluids can impact the body’s functions.
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