This clinical trial focuses on patients with Atrial Fibrillation who have undergone a procedure called Left Atrial Appendage Closure and are receiving kidney dialysis treatment. The study aims to find the best blood-thinning medication strategy after this heart procedure to prevent blood clots while minimizing bleeding risks.
The study will test two blood-thinning medications: acetylsalicylic acid (commonly known as aspirin) and clopidogrel. These medications help prevent blood clots from forming. Both medications are taken as tablets by mouth. The study will compare different durations of taking these medications, including using both medications together for different periods versus using just one medication.
Patients who participate will be monitored for several important health outcomes, including stroke, blood clots, bleeding events, and heart-related complications. The study will also look at brain function using MRI scans and cognitive tests to ensure the treatment approach is safe and effective. The medications will be given in specific doses – 75 mg daily for each medication – and patients will be followed for several months to evaluate the safety and effectiveness of different medication combinations.



Poland