This clinical trial is focused on patients undergoing a type of brain surgery called a craniotomy for a condition known as a supratentorial mass, which refers to a growth located in the upper part of the brain. The study aims to compare two different methods of pain management during this surgery: the Sphenopalatine Ganglion Block and the Scalp Block. These methods involve numbing specific areas to help manage pain and other responses during the procedure. The main goal is to observe changes in the body’s responses, such as heart rate and blood pressure, when a special headrest is used during surgery.
Participants in the study will receive one of the two pain management methods, and their responses will be monitored throughout the surgery. The study will also look at other factors, such as the level of pain relief, the need for additional pain medication like morphine, and any side effects that may occur. The medications used in this study include morphine hydrochloride, methylprednisolone, sodium chloride, propofol, lidocaine hydrochloride monohydrate, remifentanil, paracetamol, etoricoxib, cisatracurium besilate, and levobupivacaine.
The trial is designed to ensure that neither the participants nor the researchers know which pain management method is being used, a process known as a double-blind study. This helps to ensure that the results are unbiased. The study will monitor participants’ recovery, including their level of comfort and satisfaction, and any side effects they may experience during their hospital stay. The trial is expected to run until 2026, with recruitment starting in 2024.
Belgium 
