Non-steroidal aromatase inhibitors are medications that lower estrogen levels in the body. They work by blocking an enzyme called aromatase, which helps produce estrogen. These medications are commonly used to treat hormone receptor-positive breast cancer.

CDK4/6 inhibitors are targeted therapy medications that work by blocking specific proteins called CDK4 and CDK6, which help cancer cells grow and divide. These medications are used in combination with hormone therapy to treat hormone receptor-positive breast cancer.

Fulvestrant is a hormone therapy medication that blocks and degrades estrogen receptors in cancer cells. It works differently from aromatase inhibitors and is often used when breast cancer has progressed after other hormone treatments. It’s given as an injection and helps slow down or stop the growth of hormone receptor-positive breast cancer.

Breast Cancer – A disease that begins when cells in the breast tissue start to grow out of control. It typically starts in either the ducts that carry milk to the nipple or the glands that make breast milk. As the cancer cells multiply, they can form a tumor that can often be felt as a lump or seen on an x-ray. The cancer cells can spread into surrounding breast tissue and potentially to other parts of the body. This disease can occur in both women and men, though it’s much more common in women. Breast cancer may be influenced by various factors including genetic, hormonal, and environmental components.