This clinical trial is focused on the treatment of suicidal ideation, which refers to having thoughts about or an unusual preoccupation with suicide. The study will use a treatment involving a mixture of two gases: nitrous oxide and oxygen, known as KALINOX 50%/50%. This mixture is a type of medicinal gas that is inhaled. Another medicinal gas, Medical Air, which contains nitrogen and oxygen, will also be used in the study.
The purpose of the study is to evaluate whether inhaling the nitrous oxide and oxygen mixture can reduce suicidal thoughts. Participants will inhale the gas mixture for one hour while they are in the emergency department. The study will monitor the intensity of suicidal thoughts four hours after the inhalation. The study will also assess the participants’ symptoms over a period of time, including at 24 hours, 48 hours, one week, and one month after the initial treatment.
Throughout the study, various assessments will be conducted to measure changes in suicidal thoughts, depressive symptoms, and anxiety levels. These assessments will help determine the overall improvement in the participants’ condition. The study aims to provide insights into the potential benefits of using this gas mixture as a treatment for individuals experiencing suicidal thoughts.



France