Centre Hospitalier National D’Ophtalmologie Quinze-Vingts

Neuro-ophthalmology

The clinical research activity is centered on acute anterior ischemic optic neuropathy, with attention to visual outcomes in the setting of Giant Cell Arteritis and Horton’s disease.

  • Optic nerve ischemia
  • Visual impairment
  • Ischemic optic neuropathy

Interest in this area reflects a focus on conditions affecting the optic nerve and acute loss of vision.

Inflammatory vasculitis

The sponsor is involved in research on giant cell arteritis, with emphasis on its ocular complications and the inflammatory mechanisms linked to vascular injury.

  • Giant cell arteritis
  • Systemic vasculitis
  • Arteritic ocular disease

This area connects vascular inflammation with sight-threatening ischemic events.

Immunomodulatory therapy

Research activity includes the use of tocilizumab alongside corticosteroid treatment for inflammatory eye disease associated with vasculitis.

  • Interleukin-6 inhibition
  • Biologic therapy
  • Steroid-based treatment

The therapeutic interest lies in controlling immune-mediated vascular inflammation to support ocular recovery.

Acute vision-threatening disease

The trial portfolio addresses urgent ophthalmic conditions requiring close clinical management, particularly disorders with rapid onset and high risk of permanent visual loss.

  • Ocular ischemia
  • Acute visual loss
  • Eye disease in vasculitis

Research in this domain is directed toward preserving visual function in inflammatory ischemic syndromes.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on the Effectiveness of Tocilizumab, Methylprednisolone, and Prednisone for Patients with Acute Anterior Ischemic Optic Neuropathy in Giant Cell Arteritis

    Not recruiting

    2 1 1 1
    France