Retinal Disease and Geographic Atrophy
Annexon Inc. is active in dry age-related macular degeneration with geographic atrophy, focusing on visual function, visual acuity, and the preservation of retinal integrity.
- Dry age-related macular degeneration
- Geographic atrophy
- Visual acuity
- Intravitreal therapy
The sponsor’s ophthalmic research reflects interest in retina-targeted treatment for progressive degenerative eye disease.
Autoimmune Hematology and Cold Agglutinin Disease
Annexon Inc. also studies primary cold agglutinin disease, a rare autoimmune hemolytic disorder marked by complement-driven red blood cell destruction and related hematologic complications.
- Primary cold agglutinin disease
- Autoimmune hemolytic anemia
- Complement-mediated disease
- Hematology
This area of work places emphasis on immune dysregulation and blood-related disease mechanisms.
Complement Biology
The sponsor’s clinical portfolio is centered on complement pathway modulation, spanning both ocular and hematologic conditions linked to inflammatory tissue injury.
- Complement inhibition
- Inflammatory injury
- Immune-mediated pathology
Research activity in this domain connects innate immunity with disease-specific therapeutic development.


