Orthopaedic infection and prosthetic joint infection
Clinical research at Centre Hospitalier De Tourcoing includes adult cases of staphylococcal prosthetic joint infection managed with debridement, antibiotics and implant retention (DAIR), with attention to infections involving retained joint prostheses.
- Staphylococcus aureus
- Coagulase-negative staphylococci (CoNS)
- Methicillin-susceptible and methicillin-resistant strains
- Implant retention strategies
The sponsor’s research interest centers on infection control in the setting of retained orthopaedic hardware, with emphasis on staphylococcal pathogens and post-surgical joint infection management.
Antibacterial therapy for device-related infection
Trials supported by the hospital focus on oral treatment options for biofilm-associated infection, particularly comparing rifabutin with rifampicin in the context of prosthetic joint infection.
- Rifabutin
- Rifampicin
- Oral antibiotic therapy
- Biofilm-active treatment
This area reflects a therapeutic interest in antimicrobial options suited to persistent implant-associated infection and long-term management after orthopaedic surgery.
Musculoskeletal surgery and infection management
The clinical research portfolio includes patients treated following debridement and preservation of the prosthetic implant, linking surgical care with targeted antimicrobial treatment in musculoskeletal infection.
- Debridement
- Prosthesis preservation
- Orthopaedic implant infection
- Post-operative infection care
Research interest is concentrated on the clinical setting where surgical source control and antibiotic selection intersect in the treatment of infected joint replacements.
Multicentre infectious disease research
The sponsor participates in collaborative studies involving multiple research sites, supporting clinical investigation in infectious diseases across a broader hospital network.
- Multicentre collaboration
- Adult infectious disease
- Hospital-based research
- Clinical evaluation of antibiotics
This research activity is anchored in hospital care for adults with complex staphylococcal infection requiring coordinated clinical oversight.
