Cardiology
Clinical research at Krakowski Szpital Specjalistyczny Im. Sw. Jana Pawla II centers on heart failure, with a specific focus on heart failure with moderately reduced ejection fraction (HFmrEF) in the setting of ischemic heart disease.
- Ischemic cardiomyopathy
- Left ventricular function
- Cardiac remodeling
The sponsor’s active trial portfolio reflects interest in the structural and functional changes of the left ventricle in patients with symptomatic myocardial impairment.
Cardiac Imaging
The trial activity includes evaluation of magnetic resonance imaging (MRI) to assess ventricular size and function, indicating a research interest in advanced imaging markers for cardiac remodeling.
- Left ventricular end-systolic volume
- Myocardial structure
- Functional ventricular assessment
This imaging-based focus supports detailed assessment of treatment-related changes in cardiac performance and chamber geometry.
Pharmacotherapy for Heart Failure
The sponsor is involved in comparative research on heart failure therapies, with attention to angiotensin receptor-neprilysin inhibition and angiotensin-converting enzyme inhibition in patients with ischemic HFmrEF.
- Sacubitril/valsartan
- Ramipril
- Neurohormonal modulation
Therapeutic interest is directed toward medical management strategies that influence ventricular remodeling and systolic performance in chronic heart failure.
