Transplant Immunology
Clinical research in liver transplantation with attention to graft rejection and immune tolerance in A2-mismatch transplant settings.
- Prevention of liver transplant rejection
- Allogeneic immune regulation
- Post-transplant immunological compatibility
The sponsor’s transplant-focused work centers on immune-mediated complications that affect organ acceptance and long-term transplant outcomes.
Systemic Sclerosis
Research activity includes diffuse cutaneous systemic sclerosis, with emphasis on the immune and fibrotic disease processes that drive skin and internal organ involvement.
- Diffuse cutaneous systemic sclerosis (dcSSc)
- Fibrosis-related immune disease
- Autoimmune connective tissue disorders
This area reflects a therapeutic interest in severe systemic autoimmune disease with progressive tissue remodeling.
Rheumatology
The sponsor is also active in rheumatoid arthritis, particularly difficult-to-manage disease forms associated with persistent inflammation and treatment resistance.
- Difficult to treat rheumatoid arthritis (D2TRA)
- Chronic inflammatory arthritis
- Autoimmune joint disease
Its rheumatology portfolio focuses on immune-driven joint disease where durable control of inflammation remains a key therapeutic need.
Cell-Based Immunotherapy
Across its clinical program, the company is developing cell therapy approaches aimed at modifying pathogenic immune responses in both autoimmune and transplant-related conditions.
- Engineered immune cell therapies
- Targeted immunomodulation
- Immune tolerance restoration
This therapeutic domain links the sponsor’s work in autoimmunity and transplant medicine through immune system reprogramming.
