The Brigham And Women’s Hospital Inc.

Cardiology and Acute Heart Failure

Research activity is centered on acute heart failure, with attention to hospitalized patients and the transition from inpatient stabilization to ongoing cardiovascular care.

  • Heart failure management
  • Cardiovascular death
  • Worsening heart failure

The trial portfolio reflects a focus on clinically significant outcomes in patients recovering from an acute decompensated cardiac event.

Hospital-based cardiovascular care

The sponsor’s research interest includes treatment strategies initiated during hospitalization, with emphasis on patients stabilized after an acute cardiac admission.

  • In-hospital initiation of therapy
  • Post-stabilization care
  • Clinical outcomes in hospitalized patients

This area aligns with the management of high-risk patients within acute care settings at the point of discharge planning and early recovery.

Cardiovascular therapeutics

Clinical research is directed toward dapagliflozin in the context of heart failure, with interest in its role in reducing major cardiovascular events.

  • SGLT2 inhibitor therapy
  • Cardiovascular event prevention
  • Heart failure outcomes

The therapeutic focus is on evidence generation for pharmacologic management of patients with acute cardiac instability.

Multicenter clinical collaboration

Research is conducted across multiple collaborating sites and countries, supporting investigation in a broader cardiovascular disease population.

  • Collaborative research networks
  • International site participation
  • Hospital-based enrollment

The sponsor’s clinical activity is linked to coordinated research in acute care cardiology across several active centers.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study of dapagliflozin effects in patients hospitalized with acute heart failure

    Not recruiting

    1 1 1
    Czechia Hungary Poland