Champalimaud Clinical Centre

Breast Cancer Immuno-Oncology

Clinical research at the Champalimaud Clinical Centre includes studies in triple-negative breast cancer, with attention to tumour-infiltrating lymphocytes, immune activation, and checkpoint inhibitor-based treatment strategies.

  • Triple-negative breast cancer
  • Immunotherapy and chemotherapy
  • T-cell subpopulations
  • Tumour immune microenvironment

The centre’s breast cancer studies focus on locally advanced and high-risk disease, with interest in identifying immune-related features linked to treatment response.

Ovarian Cancer Treatment Guidance

The sponsor is involved in relapsed ovarian cancer research, including work on treatment selection using predictive approaches intended to support therapeutic decision-making in oncology.

  • Relapsed ovarian cancer
  • Predictive treatment models
  • Progression-free survival
  • Standard-of-care comparison

These studies reflect an interest in linking clinical outcomes with tools that may help guide care in recurrent disease.

Metastatic Breast Cancer and Symptomatic Disease

Research activity also extends to metastatic breast cancer, including patients with malignant pleural effusion and ascites, where the focus is on treatment effectiveness and disease control.

  • Metastatic breast cancer
  • Malignant pleural effusion
  • Ascites
  • Oncology supportive disease settings

The centre’s interest in this area covers advanced disease presentations and their relevance to survival outcomes and treatment choice.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

  • Study on zAvatar Test for Treatment Decisions in Relapsed Ovarian Cancer and Metastatic Breast Cancer Using Palbociclib and Drug Combination for Eligible Patients

    Recruiting

    1 1 1 1
    Portugal
  • Study on Pembrolizumab with Chemotherapy for Early-Stage Triple-Negative Breast Cancer in Patients with High TILs

    Recruiting

    1 1 1
    Investigated diseases:
    Portugal