Burn Injury and Surgical Care
Clinical research activity is centered on burn injury, with attention to the perioperative management of patients undergoing burn excisional surgery and the associated risks of blood loss and transfusion needs.
- Burn excision
- Blood loss management
- Allogeneic transfusion
This area reflects a focus on surgical care in severe thermal trauma and the haemostatic challenges linked to operative treatment.
Haemostasis and Fibrinolysis
Research interest includes the study of fibrinolysis during operative treatment for burns, with emphasis on understanding coagulation-related changes that may influence surgical bleeding.
- Fibrinolytic activity
- Coagulation balance
- Intraoperative bleeding
The sponsor’s clinical activity in this domain is linked to improving knowledge of haemostatic responses in major burn surgery.
Antifibrinolytic Therapy
The trial portfolio includes interest in tranexamic acid as a therapy relevant to surgical blood conservation in patients with burn-related operative needs.
- Tranexamic acid
- Blood conservation
- Surgical haemorrhage
This therapeutic domain is tied to reducing operative blood loss in a specialised trauma setting.
Hospital-based Clinical Research
As a hospital-based sponsor in Rotterdam, the research activity is concentrated within an acute care environment involving collaborating sites in the Netherlands.
- Acute care
- Multisite collaboration
- Specialist surgical services
The clinical setting supports focused investigation of perioperative issues in patients with severe burns.
