Groupe Hospitalier Universitaire Paris Psychiatrie Et Neuroscience

Neurodegenerative disease

Clinical research in Alzheimer disease focuses on disease progression, cognitive decline, and the relationship between microglial activation, tau pathology, and synaptic density using positron emission tomography imaging.

  • Alzheimer disease
  • Cognitive impairment
  • Neuroinflammation
  • Synaptic loss

Research activity also includes biomarker-oriented work in early Alzheimer disease and longitudinal assessment of neurological deterioration.

Psychiatry and psychosis

Trials in early psychosis, ultra high risk of psychosis, and first episode psychosis examine personalised care, functional recovery, and digital cognitive support, with additional interest in treatment-resistant depression.

  • Early psychosis
  • Ultra high risk of psychosis
  • First episode psychosis
  • Treatment-resistant depression

The sponsor also studies global functioning, neuropsychiatric symptoms, and psychotherapeutic support in mood and psychotic disorders.

Neurovascular injury

Research in aneurysmal subarachnoid hemorrhage addresses neurological recovery, functional outcome, and post-hemorrhagic disability in patients with acute cerebrovascular injury.

  • Aneurysmal subarachnoid hemorrhage
  • Neurological outcome
  • Functional recovery
  • Acute brain injury

These studies place emphasis on longer-term disability assessment and recovery after severe vascular events affecting the brain.

Eating and metabolic disorders

Clinical work in anorexia nervosa explores symptom improvement and neurobiological mechanisms relevant to severe restrictive eating disorders.

  • Anorexia nervosa
  • Eating disorder symptoms
  • Neurocognitive mechanisms

This area connects psychiatric care with investigations into behavioural and biological factors involved in disordered eating.

Experimental neuroscience in healthy volunteers

Studies in healthy subjects examine learning dynamics, noradrenergic system function, pupil diameter, and electroencephalographic responses to better understand normal cognitive processing.

  • Healthy subjects
  • Learning dynamics
  • Noradrenergic system
  • EEG responses

These investigations support translational neuroscience across cognitive and psychiatric domains.

Want to learn more about this study or check if you can participate? Contact us.

Matched clinical trials

Unfortunately, we did not find any clinical trials matching the selected criteria. Try changing the filter settings or broadening the search criteria to see more available research participation opportunities.