Respiratory Failure and Acute Respiratory Distress Syndrome
Clinical research in acute hypoxemic respiratory failure and ARDS focuses on severe infection-related respiratory compromise, with interest in ventilator-free survival and other patient-centered outcomes in critically ill adults.
- Acute hypoxemic respiratory failure
- Acute respiratory distress syndrome
- Infection-associated critical illness
- Mechanical ventilation outcomes
The respiratory portfolio also includes work relevant to systemic and pulmonary infections, including COVID-19-associated respiratory disease.
Hepatology and Liver Disease
Research activity spans advanced cirrhosis, decompensated liver disease, and metabolic associated fatty liver disease with prediabetes, with attention to disease progression and liver-related complications.
- Decompensated cirrhosis
- Metabolic associated fatty liver disease
- Prediabetes
- Liver decompensation
Additional interest extends to fecal microbiome transplantation and non-invasive liver imaging for tracking fatty liver regression.
Cardiometabolic and Cardio-Oncology Assessment
The sponsor supports studies of cardiovascular alterations linked to cirrhosis, diabetes mellitus, and cardiotoxic treatments, with emphasis on early identification of subclinical myocardial involvement.
- Cardiovascular alterations
- Diabetes mellitus
- Cardiotoxic treatments
- Subclinical myocardial involvement
Its cardiovascular research also intersects with metabolic disease and liver disease, reflecting interest in overlapping systemic complications.
Psychiatry and Schizophrenia Spectrum Disorders
Clinical research includes first psychotic episode, schizophrenia, and treatment-resistant schizophrenia, with a focus on symptom reduction, treatment continuation, and biological predictors of response.
- First psychotic episode
- Schizophrenia
- Treatment-resistant schizophrenia
- Multi-omics biomarkers
Work in this area also includes systems biology and treatment-response profiling in early psychosis.
Infectious Disease and HIV
The sponsor has research interest in HIV, including vaccine-related clinical investigation, alongside broader infectious disease themes that connect with respiratory and immunological disorders.
- Human immunodeficiency virus
- Vaccine immunogenicity
- Infectious disease
This area complements its work in infection-triggered respiratory failure and immune-mediated complications of chronic disease.
