Muscular Dystrophy Research
Edgewise Therapeutics Inc. focuses on Becker muscular dystrophy, including BMD in both adult and adolescent populations, with additional interest in related limb-girdle muscular dystrophy subtypes.
- Becker muscular dystrophy
- Adolescent neuromuscular disease
- Limb-girdle muscular dystrophy
The sponsored studies examine muscle integrity, skeletal muscle function, and markers linked to muscle damage in these inherited disorders.
Neuromuscular Disease Biomarker Studies
The sponsor supports research in broader neuromuscular disease settings, with attention to circulating indicators of disease activity and tissue injury.
- Serum creatine kinase
- Biomarkers of muscle damage
- Clinical response assessment
These trials include measurement of CK and other biomarker changes in adults with muscular dystrophy and related muscle disorders.
Metabolic Myopathy and Muscle Energy Disorders
Edgewise Therapeutics also funds studies in McArdle disease, reflecting interest in inherited disorders that affect muscle metabolism and exercise tolerance.
- McArdle disease
- Muscle metabolism
- Exercise-related muscle symptoms
Research in this area addresses the safety profile of treatment in adults with metabolic muscle disease and associated biomarker changes.
Long-term Treatment in Chronic Muscle Disease
The clinical portfolio includes extended follow-up in people living with chronic muscle disease, with emphasis on ongoing tolerability and sustained disease monitoring.
- Long-term safety
- Chronic neuromuscular disorders
- Extended treatment exposure
This area covers adult and adolescent participants across inherited muscle conditions managed in multi-site, international clinical research.
